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Correspondence
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Volume 330:1317-1318 May 5, 1994 Number 18
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Liver Transplantation in Hepatitis B

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 by Samuel, D.
To the Editor: Samuel et al. (Dec. 16 issue)1 report the results of a major retrospective multicenter study of liver transplantation in European patients with hepatitis B virus (HBV) infection. Of great clinical importance is the observed reduction in the risk of recurrence of HBV in recipients of liver allografts who received long-term ( >= 6 months) passive immunoprophylaxis with anti-hepatitis B surface antigen; no benefit was seen with short-term (2 months) immunoprophylaxis.

The mean (±SE) length of time to HBV recurrence was 3.0 ±2.6 months in patients receiving short-term immunoprophylaxis, 3.2 ±2.7 in those not given immunoprophylaxis, and 8.6 ±6.8 . . . [Full Text of this Article]

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