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Volume 330:1324-1325 May 5, 1994 Number 18

Human Herpesviruses

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Edited by Bernard Roizman, Richard J. Whitley, and Carlos Lopez. 433 pp., illustrated. New York, Raven Press, 1993. $90. ISBN 0-7817-0024-8.

This is an excellent book for scientists, researchers, microbiologists, and infectious-disease experts interested in the molecular biology, virology, epidemiology, and clinical manifestations of the herpesviruses. This important group of human viruses is remarkably interesting in that lytic infection destroys cells and concomitantly causes severe illness. But herpesviruses also induce latent, nonproductive infection and persistent slow infection. Moreover, reactivation of a latent virus leading to lytic infection may occur. The clinical implications of persistent infection and herpesvirus reactivation are incompletely understood.

Herpesviruses are approximately 100 nm in diameter, contain 162 capsomers, and consist of a lipid envelope, a tegument between the . . . [Full Text of this Article]




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