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The skepticism that once prevailed when the topic of autoimmunity came up in a discussion, or when a "so-called" autoimmune disease entered the differential diagnosis, is difficult to appreciate today. The dogma of the time -- an era that began around 1930 and ended, finally, around 1960 -- was that an antibody could not be an autoantibody. This assumption swayed otherwise reasonable people to invent labels like "erythrocyte-coating substances," even though they knew that those "substances" were antibodies.
"So-called" began disappearing from the beginning of "autoimmune disease" about 35 years ago; one interesting reason for the new attitude was the
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