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The theme of this collection of chapters is advertised as "multiple systems organ failure." The syndrome is described as developing in 15 percent of patients admitted to intensive care units and as having a mortality rate exceeding 50 percent. It is an open question whether the syndrome has become more widely recognized because patients survive longer in intensive care settings as a result of more aggressive treatment of acute problems affecting individual organs. The subtitle of this book -- "Hepatic Regulation of Systemic Host Defense" -- is not entirely accurate or convincing in its implication that there is a sole
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