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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 330:1739-1746 June 16, 1994 Number 24
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Case 24-1994— A Two-Year-Old Boy with Thrombocytopenia, Leukocytosis, and Hepatosplenomegaly
Cathy G. Rosenfield, and Mark A. Kaplan

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Presentation of Case

A two-year-old boy was admitted to the hospital because of thrombocytopenia, leukocytosis, and hepatosplenomegaly.

The boy had been born of an uncomplicated full-term pregnancy and delivery, with a birth weight of 3.5 kg. He was in excellent health until two or three weeks before admission, when a cough and coryza developed. One week before admission, a physician diagnosed otitis media and prescribed amoxicillin, with improvement of the symptoms; the child was playful and happy, although he remained warm to the touch. Three days before admission, a petechial rash appeared.

Two days before entry, the patient was admitted to another hospital, . . . [Full Text of this Article]

Differential Diagnosis

Clinical Diagnoses

Dr. Cathy G. Rosenfield's Diagnosis

Pathological Discussion

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