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Correspondence
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Volume 330:1759-1760 June 16, 1994 Number 24
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Oral Azole Drugs as Systemic Antifungal Therapy

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 by Como, J. A.
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To the Editor: The review of oral azole drugs for systemic antifungal therapy, by Como and Dismukes (Jan. 27 issue),1 was informative but lacked a discussion of the use of these agents in children. Clinicians who treat children have long been seeking an alternative to amphotericin B and have started using azole agents despite the lack of data on the pharmacokinetics, safety, and efficacy of these drugs in children. Ketoconazole is the azole most familiar to clinicians caring for children and is currently the only oral agent for which there is an established dose for children (5 to 10 mg . . . [Full Text of this Article]

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