Systemic Lupus Erythematosus (SLE) is defined by its clinicalfeatures and by the almost invariable presence in the bloodof antibodies directed against one or more components of cellnuclei. Certain manifestations seem to be associated with thepresence of different antinuclear antibodies and genetic markers,which suggests that SLE may be a family of diseases. However,clinical presentations frequently overlap, and there is currentlyno conclusive evidence that SLE is more than a single disorderwith a broad range of manifestations, the expression of whichmay be influenced by the patient's genetic background. Occasionallypatients have features of both . . . [Full Text of this Article]
Diagnosis
Drug-Induced Lupus Erythematosus
Clinical Course
Pathogenesis
Clinical Characteristics
Treatment
Conclusions
Source Information
From Harvard Medical School and Massachusetts General Hospital, Boston.
Address reprint requests to Dr. Mills at Massachusetts General Hospital, Ambulatory Care Center, Boston, MA 02114.
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