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Previous Volume 330:1905-1906 June 30, 1994 Number 26 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: The study by Blanche et al. (Feb. 3 issue)¹ confirms the bimodal pattern of AIDS in newborns and shows a clear correlation between the survival of the infant and the severity of disease in the mother. The authors hypothesize that advanced maternal disease could result in transmission of a larger viral inoculum, increased pathogenicity of the viral strains, or earlier transmission in utero. However, none of these explain how infection of newborns with human immunodeficiency virus type 1 (HIV-1) can evolve into AIDS over a few months.

Analysis of HIV-1-specific T-cell responses of newborns shows that fetal . . . [Full Text of this Article]

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