Infection of a Laboratory Worker with Simian Immunodeficiency Virus
Rima F. Khabbaz, Walid Heneine, J. Richard George, Bharat Parekh, Thomas Rowe, Toni Woods, William M. Switzer, Harold M. McClure, Michael Murphey-Corb, and Thomas M. Folks
Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.
Simian immunodeficiency viruses (SIVs) are primate lentivirusesthat are morphologically similar and biologically related tohuman immunodeficiency viruses (HIVs)1,2,3,4. SIVs naturallyinfect some nonhuman primate species, such as African greenmonkeys and sooty mangabey monkeys, without causing immunodeficiency.In contrast, experimental SIV infection of other susceptibleprimate species, such as macaques, can cause chronic wastingsyndromes and a disease similar to the human acquired immunodeficiencysyndrome (AIDS)5,6,7,8,9,10. Because of the similarities betweenthe human and nonhuman lentiviruses, SIV and its susceptibleprimate host have become the principal model for studying thepathogenesis of AIDS and developing an HIV . . . [Full Text of this Article]
Methods
Case Report
Results
Discussion
Source Information
From the Retrovirus Diseases Branch, Division of Viral and Rickettsial Diseases (R.F.K., W.H., T.R., T.W., W.M.S., T.M.F.), and the Laboratory Investigations Branch, Division of HIV/AIDS, National Center for Infectious Diseases (J.R.G., B.P.), Centers for Disease Control and Prevention, Atlanta; Yerkes Regional Primate Research Center, Emory University, Atlanta (H.M.M.); and Tulane Regional Primate Center, Tulane University, Covington, La. (M.M.-C.).
Address reprint requests to Dr. Khabbaz at the Centers for Disease Control and Prevention, Mailstop G-03, 1600 Clifton Rd., Atlanta, GA 30333.
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