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Previous Volume 330:283-284 January 27, 1994 Number 4 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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A rare disease merits general attention if it is associated with extraordinary clinical manifestations, unusual laboratory findings, or an instructive molecular defect. Paroxysmal nocturnal hemoglobinuria (PNH) has all three. Its clinical hallmark, black urine on arising from sleep, is graphic testimony to intravascular hemolysis during the night. Even more peculiar is the hemolysis that occurs after blood from a patient with PNH is mixed with acidified serum or ordinary table sugar. The molecular abnormality in PNH, described by Miyata et al. in this issue of the Journal (see pages 249 to 255), not only informs us about this unusual disease . . . [Full Text of this Article]

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This article has been cited by other articles:

• Yeh, E. T.H., Schwartz, R. S. (1994). The GPI Tail: Correction. NEJM 330: 942-943 [Full Text]