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Previous Volume 330:466-468 February 17, 1994 Number 7 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Hypothyroidism in neonates and very young infants is usually caused by thyroid dysgenesis associated with an absent, ectopic, or hypoplastic gland¹. It can be detected by neonatal screening, even if it is not clinically evident at that time. Although this condition is usually permanent, it can be transient, as it is, for example, in infants of mothers with chronic autoimmune thyroiditis^2,3. In these infants transplacental passage of maternal thyrotropin-receptor antibodies inhibits the action of thyrotropin on the infant's thyroid gland until the antibodies are metabolized by the infant during the first several weeks of life^2,3,4.

In young . . . [Full Text of this Article]

Methods

Case Reports

Patient 1

Patient 2

Patient 3

Patient 4

Discussion

Source Information

From the Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh (T.P.F.); the Department of Pediatrics, Georgetown University Medical Center, Washington, D.C. (V.A.); the Department of Pediatrics, University of Vermont College of Medicine, Burlington (K.C.C.); and the Department of Pediatrics, Michigan State University, Kalamazoo Center for Medical Studies, Kalamazoo (M.B.D.).

Address reprint requests to Dr. Foley at Children's Hospital of Pittsburgh, 3705 Fifth Ave., Pittsburgh, PA 15213-2583.

References

This article has been cited by other articles:

• Foley, T. P. Jr (2004). Hypothyroidism. Pediatr. Rev. 25: 94-100 [Full Text]  
• (2003). Visual Diagnosis: Two Infants Who Have Coarse Facial Features and Growth and Developmental Delay. Pediatr. Rev. 24: 16-22 [Full Text]  
• Arii, J., Tanabe, Y., Makino, M., Sato, H., Kohno, Y. (2002). Children With Irreversible Brain Damage Associated With Hypothyroidism and Multiple Intracranial Calcifications. J Child Neurol 17: 309-313 [Abstract]