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Previous Volume 331:881 September 29, 1994 Number 13 Next

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To the Editor: Jindal et al¹ described a woman with systemic lupus erythematosus who was receiving hemodialysis and was seropositive for the human immunodeficiency virus type 1 (HIV-1) by both enzyme-linked immunosorbent assay (ELISA) and Western blotting, with a low CD4+ cell count but no evidence of HIV-1 infection by viral culture, antigen testing, and the polymerase-chain-reaction test. The authors concluded that false positive serologic results may occur in people with lupus and end-stage renal disease, perhaps related to the presence of autoantibodies. However, the authors did not explain the patient's low CD4+ cell count (130 per cubic millimeter).

We . . . [Full Text of this Article]

References

Related Letters:

False Positive Tests for HIV in a Woman with Lupus and Renal Failure
Jindal R., Solomon M., Burrows L.
Extract | Full Text  
N Engl J Med 1993; 328:1281-1282, Apr 29, 1993. Correspondence

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