To the Editor: A letter published in the April 29, 1993, issueof the Journal reported apparently false positive serologictests for human immunodeficiency virus type 1 (HIV-1) in a Haitianwoman with systemic lupus erythematosus and end-stage renaldisease1. Three serum specimens obtained at six-week intervalswere strongly reactive for HIV-1 antibodies by enzyme-linkedimmunosorbent assay (ELISA), and Western blotting revealed thefull array of HIV-1-specific bands. However, tests for serump24 antigen, culture of peripheral-blood mononuclear cells (PBMCs)for HIV-1, and a polymerase-chain-reaction (PCR) test for HIV-1DNA were all negative. The authors therefore reasoned that the. . . [Full Text of this Article]
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(1996). Antibodies reactive with HIV-1 antigens in systemic lupus erythematosus. Lupus
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[Abstract]