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Previous Volume 331:882-883 September 29, 1994 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Cannon, R. O.

To the Editor: Cannon et al. (May 19 issue)¹ stated that the frequency of chest pain in response to the antidepressant imipramine did not depend on the presence of a previous psychiatric diagnosis or on the change in the psychiatric profile during the course of the study.

Seventeen patients (28 percent) had a history of major depression, only six of whom were randomly assigned to imipramine. Only three patients (one in the imipramine group) had major depression at base line. With such small numbers, it is clear that the study would not be able to compare patients with and those . . . [Full Text of this Article]

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