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The cloning of testis-determining factor from the Y chromosomes of mice and men has led to a flurry of research. Concomitantly, it has led to a flurry of new books on these endeavors. Dr. Wachtel's book is a collection of essays on sex determination and male reproductive development, from basic research on drosophila to clinical investigations. However, its greatest emphasis is on molecular genetic studies in mice and humans. As a student of the murine Y chromosome and male reproduction, I was able to evaluate in depth chapters such as "The Mouse Y Chromosome," whereas chapters such as "Molecular Genetics
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