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Editorial
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Volume 331:942-944 October 6, 1994 Number 14
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Progress in the Management of Hyperprolactinemia

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Hyperprolactinemia is a frequent cause of amenorrhea, infertility, and galactorrhea in women and decreased libido and impotence in men. Most patients are young women, both because of the sensitivity of pituitary-gonadal function in women to inhibition by hyperprolactinemia and because its most common causes -- a prolactin-secreting pituitary adenoma (prolactinoma) and idiopathic hyperprolactinemia -- are more common in women. Other, less frequent causes are drugs, primary hypothyroidism, and non-prolactin-secreting hypothalamic or pituitary tumors that compress the pituitary stalk. Idiopathic hyperprolactinemia is diagnosed when the serum prolactin concentration is elevated with no demonstrable pituitary or hypothalamic lesions or any other recognized . . . [Full Text of this Article]

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