The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 331:952 October 6, 1994 Number 14
NextNext

Discordant Occurrence of Primary Biliary Cirrhosis in Monozygotic Twins

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
To the Editor: The cause of primary biliary cirrhosis is unknown but may be associated with an inherited abnormality of immune regulation1,2. It is not known whether abnormal genes alone will cause the disease or whether an additional triggering event is needed. Both a genetic abnormality and a triggering event are needed to cause another chronic liver disease, autoimmune chronic active hepatitis3. We report on a pair of monozygotic twins; one was healthy, and the other had advanced primary biliary cirrhosis.

The first twin, a 58-year-old woman, had had primary biliary cirrhosis for eight years (Figure 1. . . [Full Text of this Article]

References



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.