Prostate cancer is the second leading cause of death from canceramong men; 25 percent of men with prostate cancer die of thedisease1. Moreover, many patients who do not die of prostatecancer require treatment to ameliorate symptoms such as pain,bleeding, and urinary obstruction. Thus, prostate cancer isalso a major cause of suffering and of health care expenditures.
The high rate of mortality from prostate cancer may be due tolate detection. In recent studies, screening for prostate cancerhas combined the measurement of serum prostate-specific antigen(PSA) -- the most accurate single test for the . . . [Full Text of this Article]
Treatment of Patients with Clinically Localized Disease (Stage T1 or T2)
Watchful Waiting and Hormonal Therapy
Radical Prostatectomy
Salvage Therapy after Radical Prostatectomy
Radiation Therapy
Cost-Benefit Analysis of Potentially Curative Treatment
Treatment of Patients with Locally Advanced Disease (Stage T3)
Conservative Management
Radical Prostatectomy
Preoperative Hormonal Therapy and Radical Prostatectomy
Radiation Therapy
Salvage Treatment after the Failure of Radiation Therapy
Treatment of Patients with Lymph-Node Metastases
Treatment of Patients with Disseminated Disease
Hormonal Therapy
Gonadotropin-Releasing Hormone Agonists
Nonsteroidal Antiandrogens
Other Hormonal Agents
Maximal Androgen Ablation
Treatment of Patients with Disease Refractory to Hormonal Therapy
Secondary Hormonal Therapy
Palliative Radiation Therapy
Patients with Spinal Cord Compression
Cytotoxic Chemotherapy for Hormone-Refractory Disease
Anti-Growth Factor Treatment
Supportive Therapy
Current and Future Research
Source Information
From the Department of Surgery, Division of Urologic Surgery, Washington University School of Medicine, 4960 Children's Pl., St. Louis, MO 63110, where reprint requests should be addressed to Dr. Catalona.
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