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A correction has been published: N Engl J Med 1995;332(5):335.

Review Article
Drug Therapy
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Volume 331:996-1004 October 13, 1994 Number 15
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Management of Cancer of the Prostate
William J. Catalona

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 by Stone, P.
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Prostate cancer is the second leading cause of death from cancer among men; 25 percent of men with prostate cancer die of the disease1. Moreover, many patients who do not die of prostate cancer require treatment to ameliorate symptoms such as pain, bleeding, and urinary obstruction. Thus, prostate cancer is also a major cause of suffering and of health care expenditures.

The high rate of mortality from prostate cancer may be due to late detection. In recent studies, screening for prostate cancer has combined the measurement of serum prostate-specific antigen (PSA) -- the most accurate single test for the . . . [Full Text of this Article]

Treatment of Patients with Clinically Localized Disease (Stage T1 or T2)

Watchful Waiting and Hormonal Therapy

Radical Prostatectomy

Salvage Therapy after Radical Prostatectomy

Radiation Therapy

Cost-Benefit Analysis of Potentially Curative Treatment

Treatment of Patients with Locally Advanced Disease (Stage T3)

Conservative Management

Radical Prostatectomy

Preoperative Hormonal Therapy and Radical Prostatectomy

Radiation Therapy

Salvage Treatment after the Failure of Radiation Therapy

Treatment of Patients with Lymph-Node Metastases

Treatment of Patients with Disseminated Disease

Hormonal Therapy

            Gonadotropin-Releasing Hormone Agonists

            Nonsteroidal Antiandrogens

            Other Hormonal Agents

            Maximal Androgen Ablation

Treatment of Patients with Disease Refractory to Hormonal Therapy

Secondary Hormonal Therapy

Palliative Radiation Therapy

Patients with Spinal Cord Compression

Cytotoxic Chemotherapy for Hormone-Refractory Disease

Anti-Growth Factor Treatment

Supportive Therapy

Current and Future Research


Source Information

From the Department of Surgery, Division of Urologic Surgery, Washington University School of Medicine, 4960 Children's Pl., St. Louis, MO 63110, where reprint requests should be addressed to Dr. Catalona.

References


Related Letters:

Management of Cancer of the Prostate
Stone P., Phillips C., Catalona W. J.
Extract | Full Text  
N Engl J Med 1995; 332:335-336, Feb 2, 1995. Correspondence

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