FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Volume 331:1037-1043 October 20, 1994 Number 16 Next

	Full Text Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

ABSTRACT

Background The standard treatment for patients with symptomatic multivessel coronary artery disease is coronary-artery bypass grafting (CABG). Percutaneous transluminal coronary angioplasty (PTCA) is widely used as an alternative approach to revascularization, but a systematic comparison of the two procedures is needed. We compared the outcomes in patients one year after complete revascularization with CABG or PTCA.

Methods A total of 8981 patients with multivessel coronary disease were screened at eight clinical sites, and 359 patients were randomly assigned to undergo CABG (177 patients) or PTCA (182 patients). Enrollment required that complete revascularization of at least two major vessels supplying different myocardial regions be deemed clinically necessary and technically feasible.

Results Among the patients in the CABG group, an average (±SD) of 2.2 ±0.6 vessels were grafted, and among those in the PTCA group, 1.9 ±0.5 vessels were dilated. After CABG, hospitalization was longer (median, 19 days, as compared with 5 for PTCA), and Q-wave myocardial infarction in relation to the procedure was more frequent (8.1 percent, as compared with 2.3 percent after PTCA; P = 0.022), whereas in-hospital mortality did not differ significantly between the two groups (2.5 percent in the CABG group and 1.1 percent in the PTCA group). At discharge 93 percent of the patients in the CABG group were free of angina, as compared with 82 percent of those in the PTCA group (P = 0.005). During the first year of follow-up, further interventions were necessary in 44 percent of the patients in the PTCA group (repeated PTCA in 23 percent, CABG in 18 percent, and both in 3 percent) but in only 6 percent of the patients in the CABG group (repeated CABG in 1 percent and PTCA in 5 percent; P<0.001). Seventy-four percent of the patients in the CABG group and 71 percent of those in the PTCA group were free of angina one year after treatment. Exercise capacity improved similarly in both groups. However, 22 percent of the CABG group, as compared with only 12 percent of the PTCA group, did not require antianginal medication (P = 0.041).

Conclusions In selected patients with multivessel coronary disease, PTCA and CABG as initial treatments resulted in equivalent improvement in angina after one year. However, in order to achieve similar clinical outcomes, the patients treated with PTCA were more likely to require further interventions and antianginal drugs, whereas the patients treated with CABG were more likely to sustain an acute myocardial infarction at the time of the procedure.

Source Information

From the Department of Cardiology (C.W.H., J.R., W.B.) and the Institute of Mathematics and Computer Science in Medicine (J.B.), University Hospital Eppendorf, Hamburg; the Division of Cardiology, Klinikum Bogenhausen, Munich (T.I.); and Medical Clinic II, University of Mainz, Mainz (H.-J.R.) -- all in Germany. Presented in part at the 66th Scientific Session of the American Heart Association, Atlanta, Nov. 8-11, 1993.Dr. Bleifeld is deceased.Study participants are listed in the Appendix.

Address reprint requests to Dr. Hamm at the Department of Cardiology, Medical Clinic, University Hospital Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.

Full Text of this Article

Related Letters:

Coronary Angioplasty Compared with Bypass Grafting
Hartz A. J., Kuhn E. M., Doorey A. J., Fischer J. E., Leesar M. A., Joseph S. A., Prince C. R., Hamm C. W., Berger J., Kalmar P., King S. B., Hillis L. D., Rutherford J. D.
Extract | Full Text  
N Engl J Med 1995; 332:888-890, Mar 30, 1995. Correspondence

This article has been cited by other articles:

• Mack, M. J., Prince, S. L., Herbert, M., Brown, P. P., Katz, M., Palmer, G., Edgerton, J. R., Eichhorn, E., Magee, M. J., Dewey, T. M. (2008). Current clinical outcomes of percutaneous coronary intervention and coronary artery bypass grafting.. Ann. Thorac. Surg. 86: 496-503 [Abstract] [Full Text]  
• Ortiz-Perez, J. T., Rodriguez, J., Meyers, S. N., Lee, D. C., Davidson, C., Wu, E. (2008). Correspondence Between the 17-Segment Model and Coronary Arterial Anatomy Using Contrast-Enhanced Cardiac Magnetic Resonance Imaging. J Am Coll Cardiol Img 1: 282-293 [Abstract] [Full Text]  
• Carrozza, J. P. Jr. (2008). Drug-Eluting Stents -- Pushing the Envelope beyond the Labels?. NEJM 358: 405-407 [Full Text]  
• Martuscelli, E., Clementi, F., Gallagher, M. M., D'Eliseo, A., Chiricolo, G., Nigri, A., Marino, B., Romeo, F., on behalf of CABRI trialists, (2008). Revascularization strategy in patients with multivessel disease and a major vessel chronically occluded; data from the CABRI trial. Eur. J. Cardiothorac. Surg. 33: 4-8 [Abstract] [Full Text]  
• Brown, M. L., Sundt, T. M. III, Gersh, B. J. (2008). Indications for Revascularization. Card Surg Adult 3: 551-572 [Full Text]  
• Bravata, D. M., Gienger, A. L., McDonald, K. M., Sundaram, V., Perez, M. V., Varghese, R., Kapoor, J. R., Ardehali, R., Owens, D. K., Hlatky, M. A. (2007). Systematic Review: The Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Graft Surgery. ANN INTERN MED 147: 703-716 [Abstract] [Full Text]  
• Gibbons, R. J., Fihn, S. D. (2007). Coronary Revascularization: New Evidence, New Challenges. ANN INTERN MED 147: 732-734 [Full Text]  
• Javaid, A., Steinberg, D. H., Buch, A. N., Corso, P. J., Boyce, S. W., Pinto Slottow, T. L., Roy, P. K., Hill, P., Okabe, T., Torguson, R., Smith, K. A., Xue, Z., Gevorkian, N., Suddath, W. O., Kent, K. M., Satler, L. F., Pichard, A. D., Waksman, R. (2007). Outcomes of Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention With Drug-Eluting Stents for Patients With Multivessel Coronary Artery Disease. Circulation 116: I-200-I-206 [Abstract] [Full Text]  
• Rodriguez, A. E., Maree, A. O., Mieres, J., Berrocal, D., Grinfeld, L., Fernandez-Pereira, C., Curotto, V., Rodriguez-Granillo, A., O'Neill, W., Palacios, I. F. (2007). Late loss of early benefit from drug-eluting stents when compared with bare-metal stents and coronary artery bypass surgery: 3 years follow-up of the ERACI III registry. Eur Heart J 28: 2118-2125 [Abstract] [Full Text]  
• King, S. B. III, Aversano, T., Ballard, W. L., Beekman, R. H. III, Cowley, M. J., Ellis, S. G., Faxon, D. P., Hannan, E. L., Hirshfeld, J. W. Jr, Jacobs, A. K., Kellett, M. A. Jr, Kimmel, S. E., Landzberg, J. S., McKeever, L. S., Moscucci, M., Pomerantz, R. M., Smith, K. M., Vetrovec, G. W., Creager, M. A., Hirshfeld, J. W. Jr, Holmes, D. R. Jr, Newby, L. K., Weitz, H. H., Merli, G., Pina, I., Rodgers, G. P., Tracy, C. M. (2007). ACCF/AHA/SCAI 2007 Update of the Clinical Competence Statement on Cardiac Interventional Procedures: A Report of the American College of Cardiology Foundation/American Heart Association/American College of Physicians Task Force on Clinical Competence and Training (Writing Committee to Update the 1998 Clinical Competence Statement on Recommendations for the Assessment and Maintenance of Proficiency in Coronary Interventional Procedures). J Am Coll Cardiol 50: 82-108 [Full Text]  
• Bainbridge, D., Cheng, D., Martin, J., Novick, R., The Evidence-based Peri-operative Clinical Outcome, (2007). Does off-pump or minimally invasive coronary artery bypass reduce mortality, morbidity, and resource utilization when compared with percutaneous coronary intervention? A meta-analysis of randomized trials. J. Thorac. Cardiovasc. Surg. 133: 623-631 [Abstract] [Full Text]  
• Dzau, V. J., Antman, E. M., Black, H. R., Hayes, D. L., Manson, J. E., Plutzky, J., Popma, J. J., Stevenson, W. (2006). The Cardiovascular Disease Continuum Validated: Clinical Evidence of Improved Patient Outcomes: Part I: Pathophysiology and Clinical Trial Evidence (Risk Factors Through Stable Coronary Artery Disease). Circulation 114: 2850-2870 [Full Text]  
• Authors/Task Force Members, , Fox, K., Garcia, M. A. A., Ardissino, D., Buszman, P., Camici, P. G., Crea, F., Daly, C., De Backer, G., Hjemdahl, P., Lopez-Sendon, J., Marco, J., Morais, J., Pepper, J., Sechtem, U., Simoons, M., Thygesen, K., ESC Committee for Practice Guidelines (CPG), , Priori, S. G., Blanc, J.-J., Budaj, A., Camm, J., Dean, V., Deckers, J., Dickstein, K., Lekakis, J., McGregor, K., Metra, M., Morais, J., Osterspey, A., Tamargo, J., Zamorano, J. L., Document Reviewers, , Zamorano, J. L, Andreotti, F., Becher, H., Dietz, R., Fraser, A., Gray, H., Antolin, R. A. H., Huber, K., Kremastinos, D. T., Maseri, A., Nesser, H.-J., Pasierski, T., Sigwart, U., Tubaro, M., Weis, M. (2006). Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology. Eur Heart J 27: 1341-1381 [Full Text]  
• Hordijk-Trion, M., Lenzen, M., Wijns, W., de Jaegere, P., Simoons, M. L., Scholte op Reimer, W. J.M., Bertrand, M. E., Mercado, N., Boersma, E., on behalf of the EHS-CR Investigators, (2006). Patients enrolled in coronary intervention trials are not representative of patients in clinical practice: results from the Euro Heart Survey on Coronary Revascularization. Eur Heart J 27: 671-678 [Abstract] [Full Text]  
• Kaehler, J., Koester, R., Billmann, W., Schroeder, C., Rupprecht, H.-J., Ischinger, T., Jahns, R., Vogt, A., Lampen, M., Hoffmann, R., Riessen, R., Berger, J., Meinertz, T., Hamm, C. W. (2005). 13-year follow-up of the German angioplasty bypass surgery investigation. Eur Heart J 26: 2148-2153 [Abstract] [Full Text]  
• Ramanathan, K. B., Weiman, D. S., Sacks, J., Morrison, D. A., Sedlis, S., Sethi, G., Henderson, W. G. (2005). Percutaneous Intervention Versus Coronary Bypass Surgery for Patients Older Than 70 Years of Age With High-Risk Unstable Angina. Ann. Thorac. Surg. 80: 1340-1346 [Abstract] [Full Text]  
• Malenka, D. J., Leavitt, B. J., Hearne, M. J., Robb, J. F., Baribeau, Y. R., Ryan, T. J., Helm, R. E., Kellett, M. A., Dauerman, H. L., Dacey, L. J., Silver, M. T., VerLee, P. N., Weldner, P. W., Hettleman, B. D., Olmstead, E. M., Piper, W. D., O'Connor, G. T., for the Northern New England Cardiovascular Diseas, (2005). Comparing Long-Term Survival of Patients With Multivessel Coronary Disease After CABG or PCI: Analysis of BARI-Like Patients in Northern New England. Circulation 112: I-371-I-376 [Abstract] [Full Text]  
• Rodriguez, A. E., Baldi, J., Pereira, C. F., Navia, J., Alemparte, M. R., Delacasa, A., Vigo, F., Vogel, D., O'Neill, W., Palacios, I. F., on behalf of the ERACI II Investigators, (2005). Five-Year Follow-Up of the Argentine Randomized Trial of Coronary Angioplasty With Stenting Versus Coronary Bypass Surgery in Patients With Multiple Vessel Disease (ERACI II). J Am Coll Cardiol 46: 582-588 [Abstract] [Full Text]  
• Hannan, E. L., Racz, M. J., Walford, G., Jones, R. H., Ryan, T. J., Bennett, E., Culliford, A. T., Isom, O. W., Gold, J. P., Rose, E. A. (2005). Long-Term Outcomes of Coronary-Artery Bypass Grafting versus Stent Implantation. NEJM 352: 2174-2183 [Abstract] [Full Text]  
• van Domburg, R. T., Takkenberg, J. J.M., Noordzij, L. J., Saia, F., van Herwerden, L. A., Serruys, P. W.J.C., Bogers, A. J.J.C. (2005). Late Outcome After Stenting or Coronary Artery Bypass Surgery for the Treatment of Multivessel Disease: A Single-Center Matched-Propensity Controlled Cohort Study. Ann. Thorac. Surg. 79: 1563-1569 [Abstract] [Full Text]  
• van den Brule, J. M.D., Noyez, L., Verheugt, F. W.A. (2005). Risk of coronary surgery for hospital and early morbidity and mortality after initially successful percutaneous intervention. ICVTS 4: 96-100 [Abstract] [Full Text]  
• Spertus, J. A., Nerella, R., Kettlekamp, R., House, J., Marso, S., Borkon, A. M., Rumsfeld, J. S. (2005). Risk of Restenosis and Health Status Outcomes for Patients Undergoing Percutaneous Coronary Intervention Versus Coronary Artery Bypass Graft Surgery. Circulation 111: 768-773 [Abstract] [Full Text]  
• Committee Members, , Eagle, K. A., Guyton, R. A., Davidoff, R., Edwards, F. H., Ewy, G. A., Gardner, T. J., Hart, J. C., Herrmann, H. C., Hillis, L. D., Hutter, A. M. Jr, Lytle, B. W., Marlow, R. A., Nugent, W. C., Orszulak, T. A., Task Force Members, , Antman, E. M., Smith, S. C. Jr, Alpert, J. S., Anderson, J. L., Faxon, D. P., Fuster, V., Gibbons, R. J., Gregoratos, G., Halperin, J. L., Hiratzka, L. F., Hunt, S. A., Jacobs, A. K., Ornato, J. P. (2004). ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: Summary article: A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery) . J Am Coll Cardiol 44: 1146-1154 [Full Text]  
• Beatt, K J, Morgan, K P, Kapur, A (2004). Revascularisation in diabetics with multivessel coronary artery disease. Heart 90: 999-1002 [Full Text]  
• McCaul, K A, Hobbs, M S T, Knuiman, M W, Rankin, J M, Gilfillan, I (2004). Trends in two year risk of repeat revascularisation or death from cardiovascular disease after coronary artery bypass grafting or percutaneous coronary intervention in Western Australia, 1980-2001. Heart 90: 1042-1046 [Abstract] [Full Text]  
• Eagle, K. A., Guyton, R. A., Davidoff, R., Edwards, F. H., Ewy, G. A., Gardner, T. J., Hart, J. C., Herrmann, H. C., Hillis, L. D., Hutter, A. M. Jr, Lytle, B. W., Marlow, R. A., Nugent, W. C., Orszulak, T. A., Antman, E. M., Smith, S. C. Jr, Alpert, J. S., Anderson, J. L., Faxon, D. P., Fuster, V., Gibbons, R. J., Gregoratos, G., Halperin, J. L., Hiratzka, L. F., Hunt, S. A., Jacobs, A. K., Ornato, J. P. (2004). ACC/AHA 2004 Guideline Update for Coronary Artery Bypass Graft Surgery: Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery). Circulation 110: 1168-1176 [Full Text]  
• Weintraub, W S, Mahoney, E M, Zhang, Z, Chu, H, Hutton, J, Buxton, M, Booth, J, Nugara, F, Stables, R H, Dooley, P, Collinson, J, Stuteville, M, Delahunty, N, Wright, A, Flather, M D, De Cock, E (2004). One year comparison of costs of coronary surgery versus percutaneous coronary intervention in the stent or surgery trial. Heart 90: 782-788 [Abstract] [Full Text]  
• Crescenzi, G., Bove, T., Pappalardo, F., Scandroglio, A. M., Landoni, G., Aletti, G., Zangrillo, A., Alfieri, O. (2004). Clinical significance of a new Q wave after cardiac surgery. Eur. J. Cardiothorac. Surg. 25: 1001-1005 [Abstract] [Full Text]  
• Hueb, W., Soares, P. R., Gersh, B. J., Cesar, L. A. M., Luz, P. L., Puig, L. B., Martinez, E. M., Oliveira, S. A., Ramires, J. A. F. (2004). The medicine, angioplasty, or surgery study (MASS-II): a randomized, controlled clinical trial of three therapeutic strategies for multivessel coronary artery disease: One-year results. J Am Coll Cardiol 43: 1743-1751 [Abstract] [Full Text]  
• Brener, S. J., Lytle, B. W., Casserly, I. P., Schneider, J. P., Topol, E. J., Lauer, M. S. (2004). Propensity Analysis of Long-Term Survival After Surgical or Percutaneous Revascularization in Patients With Multivessel Coronary Artery Disease and High-Risk Features. Circulation 109: 2290-2295 [Abstract] [Full Text]  
• Mehran, R., Dangas, G. D., Kobayashi, Y., Lansky, A. J., Mintz, G. S., Aymong, E. D., Fahy, M., Moses, J. W., Stone, G. W., Leon, M. B. (2004). Short- and long-term results after multivessel stenting in diabetic patients. J Am Coll Cardiol 43: 1348-1354 [Abstract] [Full Text]  
• Berger, P. B., Sketch, M. H. Jr, Califf, R. M. (2004). Choosing Between Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting for Patients With Multivessel Disease: What Can We Learn From the Arterial Revascularization Therapy Study (ARTS)?. Circulation 109: 1079-1081 [Full Text]  
• Legrand, V. M.G., Serruys, P. W., Unger, F., van Hout, B. A., Vrolix, M. C.M., Fransen, G. M.P., Nielsen, T. T., Paulsen, P. K., Gomes, R. S., de Queiroz e Melo, J. M.G., Marques dos Santos Neves, J. P., Lindeboom, W., Backx, B., on behalf of the Arterial Revascularization Therap, (2004). Three-Year Outcome After Coronary Stenting Versus Bypass Surgery for the Treatment of Multivessel Disease. Circulation 109: 1114-1120 [Abstract] [Full Text]  
• Qureshi, M. A., Safian, R. D., Grines, C. L., Goldstein, J. A., Westveer, D. C., Glazier, S., Balasubramanian, M., O'Neill, W. W. (2003). Simplified scoring system for predicting mortality after percutaneous coronary intervention. J Am Coll Cardiol 42: 1890-1895 [Abstract] [Full Text]  
• Rumsfeld, J. S., Magid, D. J., Plomondon, M. E., Sacks, J., Henderson, W., Hlatky, M., Sethi, G., Morrison, D. A., Veterans Affairs Angina With Extremely Serious Ope, (2003). Health-related quality of life after percutaneous coronary intervention versus coronary bypass surgery in high-risk patients with medically refractory ischemia. J Am Coll Cardiol 41: 1732-1738 [Abstract] [Full Text]  
• Hoffman, S. N., TenBrook, J. A. Jr, Wolf, M. P., Pauker, S. G., Salem, D. N., Wong, J. B. (2003). A meta-analysis of randomized controlled trials comparing coronary artery bypass graft with percutaneous transluminal coronary angioplasty: one- to eight-year outcomes. J Am Coll Cardiol 41: 1293-1304 [Abstract] [Full Text]  
• Rodriguez, A, Rodriguez Alemparte, M, Baldi, J, Navia, J, Delacasa, A, Vogel, D, Oliveri, R, Fernandez Pereira, C, Bernardi, V, O'Neill, W, Palacios, I F (2003). Coronary stenting versus coronary bypass surgery in patients with multiple vessel disease and significant proximal LAD stenosis: results from the ERACI II study. Heart 89: 184-188 [Abstract] [Full Text]  
• Sundt, T. M. III, Gersh, B. J., Smith, H. C. (2003). Indications for Coronary Revascularization. Card Surg Adult 2: 541-559 [Full Text]  
• Willerson, J. T. (2003). Myocardial Revascularization with Cardiologic Interventional Devices. Card Surg Adult 2: 561-580 [Full Text]  
• Corr, L.A., Stables, R. (2003). Coronary revascularization: knife or catheter?. Eur Heart J Suppl 5: B43-B48 [Abstract]  
• Brener, S. J., Lytle, B. W., Schneider, J. P., Ellis, S. G., Topol, E. J. (2002). Association between CK-MB elevation after percutaneous or surgical revascularization and three-year mortality. J Am Coll Cardiol 40: 1961-1967 [Abstract] [Full Text]  
• Bertrand, M. E., Simoons, M. L., Fox, K. A.A., Wallentin, L. C., Hamm, C. W., McFadden, E., De Feyter, P. J., Specchia, G., Ruzyllo, W. (2002). Management of acute coronary syndromes in patients presenting without persistent ST-segment elevation. Eur Heart J 23: 1809-1840 [Full Text]  
• Sedlis, S. P., Morrison, D. A., Lorin, J. D., Esposito, R., Sethi, G., Sacks, J., Henderson, W., Grover, F., Ramanathan, K. B., Weiman, D., Saucedo, J., Antakli, T., Paramesh, V., Pett, S., Vernon, S., Birjiniuk, V., Welt, F., Krucoff, M., Wolfe, W., Lucke, J. C., Mediratta, S., Booth, D., Murphy, E., Ward, H., Miller, L., Kiesz, S., Barbiere, C., Lewis, D., Investigators of the Department of Veterans Affair, (2002). Percutaneous coronary intervention versus coronary bypass graft surgery for diabetic patients with unstable angina and risk factors for adverse outcomes with bypass: outcome of diabetic patients in the AWESOME randomized trial and registry. J Am Coll Cardiol 40: 1555-1566 [Abstract] [Full Text]  
• Charlson, M. E., Allegrante, J. P., McKinley, P. S., Peterson, J. C., Boutin-Foster, C., Ogedegbe, G., Young, C. R. (2002). Improving health behaviors and outcomes after angioplasty: using economic theory to inform intervention. Health Educ Res 17: 606-618 [Abstract] [Full Text]  
• Kapur, A, Malik, I S (2002). Is surgery still the preferred option for coronary revascularisation in diabetics with multivessel coronary disease?. Heart 87: 407-409 [Full Text]  
• van Domburg, R.T, Foley, D.P, Breeman, A, van Herwerden, L.A, Serruys, P.W (2002). Coronary artery bypass graft surgery and percutaneous transluminal coronary angioplasty. Twenty-year clinical outcome. Eur Heart J 23: 543-549 [Abstract] [Full Text]  
• van den Brand, M. J. B. M., Rensing, B. J. W. M., Morel, M.-a. M., Foley, D. P., de Valk, V., Breeman, A., Suryapranata, H., Haalebos, M. M. P., Wijns, W., Wellens, F., Balcon, R., Magee, P., Ribeiro, E., Buffolo, E., Unger, F., Serruys, P. W. (2002). The effect of completeness of revascularization on event-free survival at one year in the arts trial. J Am Coll Cardiol 39: 559-564 [Abstract] [Full Text]  
• Investigators of the Department of Veterans Affair, , the Angina With Extremely Serious Operative Mortal, , Morrison, D. A., Sethi, G., Sacks, J., Henderson, W., Grover, F., Sedlis, S., Esposito, R., Ramanathan, K. B., Weiman, D., Talley, J. D., Saucedo, J., Antakli, T., Paramesh, V., Pett, S., Vernon, S., Birjiniuk, V., Welt, F., Krucoff, M., Wolfe, W., Lucke, J. C., Mediratta, S., Booth, D., Barbiere, C., Lewis, D. (2002). Percutaneous coronary intervention versus coronary bypass graft surgery for patients with medically refractory myocardial ischemia and risk factors for adverse outcomes with bypass: the VA AWESOME multicenter registry: comparison with the randomized clinical trial. J Am Coll Cardiol 39: 266-273 [Abstract] [Full Text]  
• Schneider, E. C., Leape, L. L., Weissman, J. S., Piana, R. N., Gatsonis, C., Epstein, A. M. (2001). Racial Differences in Cardiac Revascularization Rates: Does "Overuse" Explain Higher Rates among White Patients?. ANN INTERN MED 135: 328-337 [Abstract] [Full Text]  
• Morrison, D. A., Sethi, G., Sacks, J., Henderson, W., Grover, F., Sedlis, S., Esposito, R., Ramanathan, K., Weiman, D., Saucedo, J., Antakli, T., Paramesh, V., Pett, S., Vernon, S., Birjiniuk, V., Welt, F., Krucoff, M., Wolfe, W., Lucke, J. C., Mediratta, S., Booth, D., Barbiere, C., Lewis, D., for the Investigators of the Department of Veteran, (2001). Percutaneous coronary intervention versus coronary artery bypass graft surgery for patients with medically refractory myocardial ischemia and risk factors for adverse outcomes with bypass: a multicenter, randomized trial. J Am Coll Cardiol 38: 143-149 [Abstract] [Full Text]  
• Smith, S. C. Jr, Dove, J. T., Jacobs, A. K., Ward Kennedy, J., Kereiakes, D., Kern, M. J., Kuntz, R. E., Popma, J. J., Schaff, H. V., Williams, D. O., Gibbons, R. J., Alpert, J. P., Eagle, K. A., Faxon, D. P., Fuster, V., Gardner, T. J., Gregoratos, G., Russell, R. O., Smith, S. C. Jr (2001). ACC/AHA guidelines for percutaneous coronary intervention (revision of the 1993 PTCA guidelines): A report of the American College of Cardiology/ American Heart Association Task Force on practice guidelines (Committee to revise the 1993 guidelines for percutaneous transluminal coronary angioplasty) endorsed by the Society for Cardiac Angiography and Interventions. J Am Coll Cardiol 37: 2239-2239 [Full Text]  
• Metzdorff, M. T., Sapirstein, W., Zuckerman, B., Dillard, J., Eisenberg, M. J., Sheppard, R., Leon, M. B., Teirstein, P. S., Moses, J. W. (2001). Intracoronary Radiotherapy for Restenosis. NEJM 344: 1796-1797 [Full Text]  
• Pell, J P, Walsh, D, Norrie, J, Berg, G, Colquhoun, A D, Davidson, K, Eteiba, H, Faichney, A, Flapan, A, Hogg, K J, Jeffrey, R R, Jennings, K, McArthur, J, Mankad, P, Oldroyd, K, Pell, A C H, Starkey, I R (2001). Outcomes following coronary artery bypass grafting and percutaneous transluminal coronary angioplasty in the stent era: a prospective study of all 9890 consecutive patients operated on in Scotland over a two year period. Heart 85: 662-666 [Abstract] [Full Text]  
• Pretre, R., Turina, M. I. (2001). Choice of Revascularization Strategy for Patients With Coronary Artery Disease. JAMA 285: 992-994 [Full Text]  
• Rodriguez, A., Bernardi, V., Navia, J., Baldi, J., Grinfeld, L., Martinez, J., Vogel, D., Grinfeld, R., Delacasa, A., Garrido, M., Oliveri, R., Mele, E., Palacios, I., O'Neill, W., for the ERACI II Investigators, (2001). Argentine randomized study: coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple-vessel disease (ERACI II): 30-day and one-year follow-up results. J Am Coll Cardiol 37: 51-58 [Abstract] [Full Text]  
• Ryan, T. J. (2001). Present-day PTCR versus CABG: a randomized comparison with a different focus and a new result. J Am Coll Cardiol 37: 59-62 [Full Text]  
• Bertrand, M.E, Simoons, M.L, Fox, K.A.A, Wallentin, L.C, Hamm, C.W, McFadden, E, de Feyter, P.J, Specchia, G, Ruzyllo, W (2000). Management of acute coronary syndromes: acute coronary syndromes without persistent ST segment elevation. Recommendations of the Task Force of the European Society of Cardiology: Recommendations of the Task Force of the European Society of Cardiology. Eur Heart J 21: 1406-1432  
• Rao, V., Borger, M. A., Weisel, R. D., Ivanov, J., Christakis, G. T., Cohen, G., Yau, T. M. (2000). INSULIN CARDIOPLEGIA FOR ELECTIVE CORONARY BYPASS SURGERY. J. Thorac. Cardiovasc. Surg. 119: 1176-1184 [Abstract] [Full Text]  
• Diegeler, A., Spyrantis, N., Matin, M., Falk, V., Hambrecht, R., Autschbach, R., Mohr, F. W., Schuler, G. (2000). The revival of surgical treatment for isolated proximal high grade LAD lesions by minimally invasive coronary artery bypass grafting. Eur. J. Cardiothorac. Surg. 17: 501-504 [Abstract] [Full Text]  
• King, S. B. III, Kosinski, A. S., Guyton, R. A., Lembo, N. J., Weintraub, W. S., for the Emory Angioplasty Versus Surgery Trial (EA, (2000). Eight-year mortality in the Emory Angioplasty versus Surgery Trial (EAST). J Am Coll Cardiol 35: 1116-1121 [Abstract] [Full Text]  
• Ambrose, J. A., Dangas, G. (2000). Unstable Angina: Current Concepts of Pathogenesis and Treatment. Arch Intern Med 160: 25-37 [Abstract] [Full Text]  
• Rankin, J. M., Spinelli, J. J., Carere, R. G., Ricci, D. R., Penn, I. M., Hilton, J. D., Henderson, M. A., Hayden, R. I., Buller, C. E. (1999). Improved Clinical Outcome after Widespread Use of Coronary-Artery Stenting in Canada. NEJM 341: 1957-1965 [Abstract] [Full Text]  
• Lewsey, J.D, Murray, G.D, Leyland, A.H, Boddy, F.A (1999). Comparing outcomes of percutaneous transluminal coronary angioplasty with coronary artery bypass grafting. Can routine health service data complement and enhance randomized controlled trials?. Eur Heart J 20: 1731-1735 [Abstract]  
• Whitlow, P. L., Dimas, A. P., Bashore, T. M., Califf, R. M., Bourassa, M. G., Chaitman, B. R., Rosen, A. D., Kip, K. E., Stadius, M. L., Alderman, E. L., for the BARI Investigators, (1999). Relationship of extent of revascularization with angina at one year in the bypass angioplasty revascularization investigation (BARI). J Am Coll Cardiol 34: 1750-1759 [Abstract] [Full Text]  
• Hueb, W. A., Soares, P. R., Almeida de Oliveira, S., Arie, S., Cardoso, R. H. A., Wajsbrot, D. B., Cesar, L. A. M., Jatene, A. D., Ramires, J. A. F. (1999). Five-Year Follow-Up of the Medicine, Angioplasty, or Surgery Study (MASS) : A Prospective, Randomized Trial of Medical Therapy, Balloon Angioplasty, or Bypass Surgery for Single Proximal Left Anterior Descending Coronary Artery Stenosis. Circulation 100: II-107-113 [Abstract] [Full Text]  
• Park, J.-W. (1999). Interventional cardiology versus minimally invasive cardiac surgery. Eur. J. Cardiothorac. Surg. 16: S117-S118 [Abstract] [Full Text]  
• Eagle, K. A., Guyton, R. A., Davidoff, R., Ewy, G. A., Fonger, J., Gardner, T. J., Gott, J. P., Herrmann, H. C., Marlow, R. A., Nugent, W. C., O'Connor, G. T., Orszulak, T. A., Rieselbach, R. E., Winters, W. L., Yusuf, S., Gibbons, R. J., Alpert, J. S., Eagle, K. A., Gardner, T. J., Garson, A. Jr., Gregoratos, G., Russell, R. O., Smith, S. C. Jr. (1999). ACC/AHA guidelines for coronary artery bypass graft surgery: A report of the American College of Cardiology/ American Heart Association task force on Practice Guidelines (Committee to revise the 1991 Guidelines for Coronary Artery Bypass Graft Surgery). J Am Coll Cardiol 34: 1262-1347 [Full Text]  
• O'Connor, G. T., Malenka, D. J., Quinton, H., Robb, J. F., Kellett, M. A. Jr., Shubrooks, S., Bradley, W. A., Hearne, M. J., Watkins, M. W., Wennberg, D. E., Hettleman, B., O'Rourke, D. J., McGrath, P. D., Ryan, T. Jr., VerLee, P., for the Northern New England Cardiovascular Diseas, (1999). Multivariate prediction of in-hospital mortality after percutaneous coronary interventions in 1994-1996. J Am Coll Cardiol 34: 681-691 [Abstract] [Full Text]  
• Goy, J.-J., Eeckhout, E., Moret, C., Burnand, B., Vogt, P., Stauffer, J.-C., Hurni, M., Stumpe, F., Ruchat, P., von Segesser, L., Urban, P., Kappenberger, L. (1999). Five-Year Outcome in Patients With Isolated Proximal Left Anterior Descending Coronary Artery Stenosis Treated by Angioplasty or Left Internal Mammary Artery Grafting : A Prospective Trial. Circulation 99: 3255-3259 [Abstract] [Full Text]  
• Kuntz, K. M., Fleischmann, K. E., Hunink, M. G.M., Douglas, P. S. (1999). Cost-Effectiveness of Diagnostic Strategies for Patients with Chest Pain. ANN INTERN MED 130: 709-718 [Abstract] [Full Text]  
• Bourassa, M. G., Kip, K. E., Jacobs, A. K., Jones, R. H., Sopko, G., Rosen, A. D., Sharaf, B. L., Schwartz, L., Chaitman, B. R., Alderman, E. L., Holmes, D. R., Roubin, G. S., Detre, K. M., Frye, R. L., for the BARI Investigators, (1999). Is a strategy of intended incomplete percutaneous transluminal coronary angioplasty revascularization acceptable in nondiabetic patients who are candidates for coronary artery bypass graft surgery?: The bypass angioplasty revascularization investigation (BARI). J Am Coll Cardiol 33: 1627-1636 [Abstract] [Full Text]  
• Bernstein, S J, Brorsson, B, Åberg, T, Emanuelsson, H, Brook, R H, Werkö, L (1999). Appropriateness of referral of coronary angiography patients in Sweden. Heart 81: 470-477 [Abstract] [Full Text]  
• Windecker, S., Maier-Rudolph, W., Bonzel, T., Heyndrickx, G., Lablanche, J.M., Morice, M.C., Muhlberger, V., Neuhaus, K.L., Piscione, F., van den Brand, M., Wijns, W., Meier, B., Working Group Coronary Circulation of the European, (1999). Interventional cardiology in Europe 1995. Eur Heart J 20: 484-495 [Abstract]  
• Kornowski, R., Mehran, R., Satler, L. F., Pichard, A. D., Kent, K. M., Greenberg, A., Mintz, G. S., Hong, M. K., Leon, M. B. (1999). Procedural results and late clinical outcomes following multivessel coronary stenting. J Am Coll Cardiol 33: 420-426 [Abstract] [Full Text]  
• Mullany, C. J., Mock, M. B., Brooks, M. M., Kelsey, S. F., Keller, N. M., Sutton-Tyrrell, K., Detre, K. M., Frye, R. L. (1999). Effect of age in the bypass angioplasty revascularization investigation (BARI) randomized trial. Ann. Thorac. Surg. 67: 396-403 [Abstract] [Full Text]  
• Hannan, E. L., Racz, M. J., McCallister, B. D., Ryan, T. J., Arani, D. T., Isom, O. W., Jones, R. H. (1999). A comparison of three-year survival after coronary artery bypass graft surgery and percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 33: 63-72 [Abstract] [Full Text]  
• Landesberg, G., Wolf, Y., Schechter, D., Mosseri, M., Weissman, C., Anner, H., Chisin, R., Luria, M. H., Kovalski, N., Bocher, M., Erel, J., Berlatzky, Y. (1998). Preoperative Thallium Scanning, Selective Coronary Revascularization, and Long-Term Survival After Carotid Endarterectomy. Stroke 29: 2541-2548 [Abstract] [Full Text]  
• DeYoung, M. B., Dichek, D. A. (1998). Gene Therapy for Restenosis : Are We Ready?. Circ. Res. 82: 306-313 [Abstract] [Full Text]  
• Moussa, I., Reimers, B., Moses, J., Di Mario, C., Di Francesco, L., Ferraro, M., Colombo, A. (1997). Long-term Angiographic and Clinical Outcome of Patients Undergoing Multivessel Coronary Stenting. Circulation 96: 3873-3879 [Abstract] [Full Text]  
• Barsness, G. W., Peterson, E. D., Ohman, E. M., Nelson, C. L., DeLong, E. R., Reves, J. G., Smith, P. K., Anderson, R. D., Jones, R. H., Mark, D. B., Califf, R. M. (1997). Relationship Between Diabetes Mellitus and Long-term Survival After Coronary Bypass and Angioplasty. Circulation 96: 2551-2556 [Abstract] [Full Text]  
• Chaitman, B. R., Rosen, A. D., Williams, D. O., Bourassa, M. G., Aguirre, F. V., Pitt, B., Rautaharju, P. M., Rogers, W. J., Sharaf, B., Attubato, M., Hardison, R. M., Srivatsa, S., Kouchoukos, N. T., Stocke, K., Sopko, G., Detre, K., Frye, R. (1997). Myocardial Infarction and Cardiac Mortality in the Bypass Angioplasty Revascularization Investigation (BARI) Randomized Trial. Circulation 96: 2162-2170 [Abstract] [Full Text]  
• Ellis, S. G., Narins, C. R. (1997). Problem of Angioplasty in Diabetics. Circulation 96: 1707-1710 [Full Text]  
• Brener, S. J., Loop, F. D., Lytle, B. W., Ellis, S. G., Cosgrove, D. M., Topol, E. J. (1997). A PROFILE OF CANDIDATES FOR REPEAT MYOCARDIAL REVASCULARIZATION: IMPLICATIONS FOR SELECTION OF TREATMENT. J. Thorac. Cardiovasc. Surg. 114: 153-161 [Abstract] [Full Text]  
• Johnson, R. G., Sirois, C., Thurer, R. L., Sellke, F. W., Cohn, W. E., Kuntz, R. E., Weintraub, R. M. (1997). Predictors of CABG Within One Year of Successful PTCA: A Retrospective, Case-Control Study. Ann. Thorac. Surg. 64: 3-7 [Abstract] [Full Text]  
• Robinson, M. C., Gross, D. R., Thielmeier, K. A., Hill, B. B., Zeman, W. F. (1997). Development of a Minimally Invasive Technique for Coronary Revascularization in a Porcine Model. Ann. Thorac. Surg. 64: 64-69 [Abstract] [Full Text]  
• Weintraub, W. S., Jones, E. L., Morris, D. C., King, S. B. III, Guyton, R. A., Craver, J. M. (1997). Outcome of Reoperative Coronary Bypass Surgery Versus Coronary Angioplasty After Previous Bypass Surgery. Circulation 95: 868-877 [Abstract] [Full Text]  
• Topol, E. J., Califf, R. M., Van de Werf, F., Simoons, M., Hampton, J., Lee, K. L., White, H., Simes, J., Armstrong, P. W. (1997). Perspectives on Large-Scale Cardiovascular Clinical Trials for the New Millennium. Circulation 95: 1072-1082 [Full Text]  
• Hlatky, M. A., Rogers, W. J., Johnstone, I., Boothroyd, D., Brooks, M. M., Pitt, B., Reeder, G., Ryan, T., Smith, H., Whitlow, P., Wiens, R., Mark, D. B., Rosen, A. D., Detre, K., Frye, R. L., The Bypass Angioplasty Revascularization Investiga, (1997). Medical Care Costs and Quality of Life after Randomization to Coronary Angioplasty or Coronary Bypass Surgery. NEJM 336: 92-99 [Abstract] [Full Text]  
• Hartz, R. S. (1996). Minimally Invasive Heart Surgery. Circulation 94: 2669-2670 [Full Text]  
• Bittl, J. A. (1996). Advances in Coronary Angioplasty. NEJM 335: 1290-1302 [Full Text]  
• Kuntz, K. M., Tsevat, J., Goldman, L., Weinstein, M. C. (1996). Cost-effectiveness of Routine Coronary Angiography After Acute Myocardial Infarction. Circulation 94: 957-965 [Abstract] [Full Text]  
• Simoons, M. L. (1996). Myocardial Revascularization -- Bypass Surgery or Angioplasty?. NEJM 335: 275-277 [Full Text]  
• Pocock, S. J., Henderson, R. A., Seed, P., Treasure, T., Hampton, J. R. (1996). Quality of Life, Employment Status, and Anginal Symptoms After Coronary Angioplasty or Bypass Surgery: 3-Year Follow-up in the Randomized Intervention Treatment of Angina (RITA) Trial. Circulation 94: 135-142 [Abstract] [Full Text]  
• Zhao, X.-Q., Brown, B. G., Stewart, D. K., Hillger, L. A., Barnhart, H. X., Kosinski, A. S., Weintraub, W. S., King, S. B. III (1996). Effectiveness of Revascularization in the Emory Angioplasty Versus Surgery Trial : A Randomized Comparison of Coronary Angioplasty With Bypass Surgery. Circulation 93: 1954-1962 [Abstract] [Full Text]