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Editorial
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Volume 331:1372-1374 November 17, 1994 Number 20
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Acute Renal Failure -- Some Progress?

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Acute renal failure is an important cause of morbidity and mortality. The annual incidence of severe acute renal failure in the United Kingdom is about 180 per million,1 but substantial renal impairment may occur in up to 5 percent of patients undergoing major surgery. Because its management is so complex, acute renal failure has a high monetary cost, and because the mortality rate is over 90 percent in some groups of patients, the cost per survivor may be astronomical. The continuing challenge, therefore, is to prevent acute renal failure and, failing that, to develop therapeutic strategies to promote the recovery . . . [Full Text of this Article]

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