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Correspondence
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Volume 331:1455-1456 November 24, 1994 Number 21
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The 1993 Pertussis Epidemic in Cincinnati

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 by Christie, C.
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To the Editor: Christie and colleagues (July 7 issue)1 document the effect of the 1993 pertussis outbreak in Cincinnati and suggest that the proportion of cases in fully vaccinated children provides evidence of "the failure of the whole-cell pertussis vaccine." However, their data prove only that pertussis vaccine is not 100 percent effective and that outbreaks of disease can occur in highly vaccinated populations. In outbreaks of any disease that can be prevented by vaccination, the proportion of cases in people who have been vaccinated will depend on both the efficacy of the vaccine and the vaccination coverage of the . . . [Full Text of this Article]

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