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Previous Volume 331:1488-1491 December 1, 1994 Number 22 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Space-occupying lesions in the brain of patients infected with the human immunodeficiency virus (HIV) are commonly due to Toxoplasma gondii infection or lymphoma¹. Multiple other infectious agents, including nocardia species and Mycobacterium tuberculosis, as well as bacterial abscesses also cause such lesions¹. Despite the increased incidence of neurosyphilis in the HIV-infected population,² with reports of both meningovascular and quaternary neurosyphilis,^2,3,4 we are aware of only two instances of space-occupying lesions of the central nervous system presumed to be due to Treponema pallidum⁵ among the hundreds of biopsy and autopsy evaluations of brain tissue from patients with the acquired . . . [Full Text of this Article]

Case Report

Methods

Detection of Treponemes by Direct Immunofluorescence Staining

Detection of T. pallidum DNA by PCR and Hybridization

Results

Pathological Findings

Immunofluorescence Staining

PCR

Discussion

Source Information

From the Department of Medicine, Division of Infectious Diseases (H.W.H., G.P.W.), and the Department of Pathology (M.P.V.), New York Medical College, Valhalla; Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany (V.W., F.A., K.W.); and the Division of Sexually Transmitted Diseases Laboratory Research, Centers for Disease Control and Prevention, Atlanta (S.A.L.).

Address reprint requests to Dr. Horowitz at Westchester County Medical Center, Division of Infectious Diseases, Rm. 209, Macy Pavilion SE, Valhalla, NY 10595.

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