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Previous Volume 331:1694-1702 December 22, 1994 Number 25 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Colon cancer is one of the most frequent cancers in men and women in the United States.¹ There is a 6 percent lifetime risk of colon cancer in the general population.¹ Approximately 160,000 new cases arise every year, and despite advances in detection and therapy, 60,000 people die of colon cancer and its complications each year.² Epidemiologic studies have implicated environmental factors in the pathogenesis of the disease. Support for these findings comes from the wide variations in the incidence of colon cancer among different populations.³ In Western societies, with diets high in fat and low in fiber, the rates . . . [Full Text of this Article]

Gastrointestinal Polyposis and Nonpolyposis Syndromes

Adenomatous Polyposis Syndromes

Familial Adenomatous Polyposis

Genetic Features of Familial Adenomatous Polyposis

Gardner's Syndrome

Screening of Kindreds with Familial Adenomatous Polyposis and Gardner's Syndrome

Turcot's Syndrome

Hamartomatous Polyposis Syndromes

Peutz-Jeghers Syndrome

Juvenile Polyposis

Cowden's Disease (Multiple Hamartoma Syndrome)

Neurofibromatosis

Hereditary Nonpolyposis Colorectal Cancer Syndromes

Genetic Features of HNPCC

Screening for HNPCC

Muir-Torre Syndrome

Variants of Familial Adenomatous Polyposis

Conclusions

Source Information

From the Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston.

Address reprint requests to Dr. Rustgi at the Gastrointestinal Unit, Jackson 7, Massachusetts General Hospital, 50 Blossom St., Boston, MA 02114.

References

Related Letters:

Gastrointestinal Polyposis and Nonpolyposis Syndromes
Samowitz W. S., Burt R. W., Leppert M., Dupuis M.J.M., Verellen-Dumoulin C., Coyle T., Ellis M. F., Whitelaw S., Rustgi A. K.
Extract | Full Text  
N Engl J Med 1995; 332:1518-1520, Jun 1, 1995. Correspondence

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