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Correspondence
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Volume 331:1717-1719 December 22, 1994 Number 25
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Heterosexual Transmission of HIV

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 by De Vincenzi, I.
To the Editor: De Vincenzi (Aug. 11 issue)1 concludes that consistent use of condoms is highly effective in preventing heterosexual transmission of the human immunodeficiency virus (HIV). However, the data analysis is flawed. First, the use of person-years as the unit of comparison for seroconversion rates does not take into account the difference between consistent and inconsistent users of condoms in the frequency of sexual contact. The author reports that the median frequency of sexual contact among the latter was twice that among the former. Once this is accounted for,2 the seroconversion rate for inconsistent users is 2.5 per 100 . . . [Full Text of this Article]

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