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Previous Volume 331:174-180 July 21, 1994 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Thyroxine therapy is given to replace thyroid hormone secretion when it is deficient (hypothyroidism) and also in certain circumstances when suppression of thyrotropin secretion is considered to be of value, such as in patients with thyroid carcinoma. It is perhaps surprising that any problems are perceived, other than compliance, with a treatment that has been available in one form or another for over a century. However, the availability of increasingly sensitive assays for thyrotropin¹ has led to controversy about the dose of thyroxine needed for replacement therapy and about the safety of long-term suppressive treatment. Other issues include whether patients . . . [Full Text of this Article]

Replacement Therapy

Overt Hypothyroidism

Subclinical Hypothyroidism

Variation in Required Dose of Thyroxine

Transient Hypothyroidism

Ischemic Heart Disease

Pregnancy

Neonatal Hypothyroidism

Suppressive Therapy

Inappropriate Thyroxine Therapy

Summary

Source Information

From the Royal Infirmary, Edinburgh EH3 9YW, Scotland, where reprint requests should be addressed to Dr. Toft.

References

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