The New England Journal of Medicine
e-mail icon  FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |    Advanced Search
Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe
 
Correspondence
PreviousPrevious
Volume 331:335-336 August 4, 1994 Number 5
NextNext

Continuous Intraarterial Measurement of Oxygenation during Aerosolized Prostacyclin Administration in Severe Respiratory Failure

Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

 Sign up for free e-toc
 

This Article
-Full Text
-Purchase this article

Tools and Services
-Add to Personal Archive
-Add to Citation Manager
-Notify a Friend
-E-mail When Cited

More Information
To the Editor: A recent report1 stimulated us to use aerosolized prostaglandin I2 (PGI2; also called prostacyclin or epoprostenol) to improve arterial oxygenation by producing selective pulmonary vasodilation in well-ventilated areas. PGI2 decreases microvascular pressure in the lung and reduces pulmonary fluid filtration and right-heart afterload2.

We report here on a 65-year-old patient with severe respiratory failure due to pneumonia (Klebsiella pneumoniae infection) and pulmonary hypertension. The chest film showed extensive bilateral interstitial infiltrates, signs of a "capillary leak syndrome," and atelectasis. Because of critically decreased oxygenation, we inserted a sensor into the left radial artery and connected . . . [Full Text of this Article]

References



HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org

Comments and questions? Please contact us.

The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.