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Editorial
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Volume 331:393-394 August 11, 1994 Number 6
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New Issues in Therapy after Renal Transplantation

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Maintaining a balance between adequate immunosuppression to prevent the rejection of an allograft and excessive immunosuppression, with its attendant risks of opportunistic infections and neoplasia, has always been the quintessential challenge for the transplantation physician. "Save the patient, not the graft" is a reasonable maxim, since renal-transplant recipients, unlike patients receiving other solid-organ grafts, have dialysis available to replace organ function. As Suthanthiran and Strom point out in this issue of the Journal,1 we have now been learning for over a decade how best to use cyclosporine, which reduces the incidence of acute rejection2 and improves graft survival at one . . . [Full Text of this Article]

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