Neurologic symptoms due to electrolyte disorders are common,occurring in patients with diarrhea, diabetes mellitus, headinjury, renal failure, and many other disorders, especiallyin infants and the elderly. The clinical syndromes of dehydrationand overhydration, often first detected in measurements of plasmasodium or osmolality, are among the most frequent causes ofthe neurologic symptoms, which include irritability, seizures,lethargy, and coma. There are multiple hormonal and neurogenicmechanisms to maintain total body water and the concentrationof solutes (osmolality) within narrow limits. Interruption ofthese homeostatic mechanisms leads to the retention or lossof either water or solute; . . . [Full Text of this Article]
Methods
Patient
Proton NMR Spectroscopy
Results
Discussion
Source Information
From the Magnetic Resonance Spectroscopy Unit, Huntington Medical Research Institutes (J.H.L., B.D.R.); and Huntington Memorial Hospital (E.A.) -- both in Pasadena, Calif.
Address reprint requests to Dr. Ross at Huntington Medical Research Institutes, 660 S. Fair Oaks Ave., Pasadena, CA 91105.
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