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Case Records of the Massachusetts General Hospital
Weekly Clinicopathological Exercises
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Volume 332:663-671 March 9, 1995 Number 10
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Case 7-1995— A 58-year-old man with common variable immunodeficiency, splenomegaly, and hemolytic anemia
J.T. Wong, and C. Girardet

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Presentation of Case

A 58-year-old man with common variable immunodeficiency, recurrent sinusitis, splenomegaly, and mild thrombocytopenia was admitted to the hospital because of severe anemia and jaundice.

He had a 10-year history of recurrent sinusitis, which responded to treatment with various antibiotics. Laboratory studies eight years before admission had led to a diagnosis of common variable immunodeficiency (Table 1). The patient received immune globulin intravenously and was given frequent courses of antibiotics to suppress bouts of acute sinusitis.

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Table 1. Laboratory Findings before Admission.

 
Thirty-eight months before admission radiographs of the abdomen revealed splenomegaly. During the next three years the platelet count gradually . . . [Full Text of this Article]

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Related Letters:

Hypogammaglobulinemia in HIV-Infected Infants
Love J. T., Shearer W. T., Wong J. T.
Extract | Full Text  
N Engl J Med 1995; 333:321-322, Aug 3, 1995. Correspondence

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