FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 332:1092-1093 April 20, 1995 Number 16 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Infection with hepatitis B virus (HBV) results in a broad spectrum of liver disease, ranging from subclinical infection to acute, self-limited hepatitis and fatal, fulminant hepatitis. Exposure to HBV, particularly when it occurs early in life, may also result in an asymptomatic carrier state that can progress to chronic active hepatitis, cirrhosis of the liver, and eventually hepatocellular carcinoma. Complex viral and host factors determine this variable clinical outcome. Fundamental questions about the biologic aspects of hepatitis B that have direct relevance to clinical practice remain unresolved. It is estimated that there are 400 to 500 million HBV carriers in . . . [Full Text of this Article]

References

This article has been cited by other articles:

• Candotti, D., Temple, J., Sarkodie, F., Allain, J.-P. (2003). Frequent Recovery and Broad Genotype 2 Diversity Characterize Hepatitis C Virus Infection in Ghana, West Africa. J. Virol. 77: 7914-7923 [Abstract] [Full Text]  
• Lee, W. M. (1997). Hepatitis B Virus Infection. NEJM 337: 1733-1745 [Full Text]  
• Poovorawan, Y., Sanpavat, S., Chumdermpadetsuk, S., Safary, A. (1997). Long term hepatitis B vaccine in infants born to hepatitis B e antigen positive mothers. Arch. Dis. Child. Fetal Neonatal Ed. 77: 47F-51 [Abstract] [Full Text]  
• Seymour, C. A (1996). Controversies in Management: Screening asymptomatic people at high risk for hepatitis C. BMJ 312: 1347-1348 [Full Text]