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Review Article
Medical Progress
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Volume 332:1144-1152 April 27, 1995 Number 17
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Hypoglycemic Disorders
F.J. Service, M.D., Ph.D.

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Hypoglycemia is a clinical syndrome with diverse causes in which low levels of plasma glucose eventually lead to neuroglycopenia. This review will be devoted to hypoglycemic disorders that do not result from the treatment of diabetes mellitus.

Glucose Counterregulation

In healthy persons, postabsorptive levels of plasma glucose stay within a narrow range (about 60 to 100 mg per deciliter [3.3 to 5.6 mmol per liter]) despite the intermittent ingestion of food. Insulin, the primary regulatory hormone that blunts postprandial hyperglycemia and maintains postabsorptive euglycemia, has its effects counterbalanced by several factors that provide a minimal level of glycemia in order to sustain . . . [Full Text of this Article]

Symptoms

Classification

Evaluation

The Healthy-Appearing Patient

Plasma Glucose Levels

            The 72-Hour Fast

            The C-Peptide Suppression and Intravenous Tolbutamide Tests

            Insulin Antibodies

            The Mixed-Meal Test

The Ill-Appearing Patient

Management

References


Related Letters:

Hypoglycemic Disorders
Piziak V.K., Cryar A. K., Rubin E., Service F. J.
Extract | Full Text  
N Engl J Med 1995; 333:1154-1155, Oct 26, 1995. Correspondence

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