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The photograph showing the hunterian chancre is superb. Also, Wong and Mihm have demonstrated classic histologic techniques with the hematoxylin-and-eosin staining and the spirochetes visualized with silver staining.
The evaluation of this disease would be enhanced, and an immediate diagnosis of a treatable disorder provided, if direct dark-field microscopy was performed on a serum specimen obtained directly from the edge of the chancre by touching a coverslip to the lesion and
References
Related Letters:
Smallpox
Magner J., Maher J. P., Aly A., Aly S., Larner A. J., Herron C. A., Kassirer J. P.
Extract |
Full Text
N Engl J Med 1996;
335:900-902, Sep 19, 1996.
Correspondence
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