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The new policy is based on several erroneous assumptions. The first is that there is more discretion on the part of investigators and greater opportunity for bias in economic and cost-effectiveness analyses than in clinical research. In fact, there is plenty of discretion in both. Discretionary decisions about which outcome measures to use in clinical research, for example, can easily determine whether one treatment is found to be
References
Related Letters:
Fraud in Breast-Cancer Trials
Fisher B., Redmond C. K., Poisson R., Broder S., Bivens L. W., Macfarlane D. K., Bernier G. M., Huet P.-M., Richer G.
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N Engl J Med 1994;
330:1458-1462, May 19, 1994.
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