Background Older persons who are hospitalized for acute illnessesoften lose their independence and are discharged to institutionsfor long-term care.
Methods We studied 651 patients 70 years of age or older whowere admitted for general medical care at a teaching hospital;these patients were randomly assigned to receive usual careor to be cared for in a special unit designed to help olderpersons maintain or achieve independence in self-care activities.The key elements of this program were a specially prepared environment(with, for example, uncluttered hallways, large clocks and calendars,and handrails); patient-centered care emphasizing independence,including specific protocols for prevention of disability andfor rehabilitation; discharge planning with the goal of returningthe patient to his or her home; and intensive review of medicalcare to minimize the adverse effects of procedures and medications.The main outcome we measured was the change from admission todischarge in the number of five basic activities of daily living(bathing, getting dressed, using the toilet, moving from a bedto a chair, and eating) that the patient could perform independently.
Results Twenty-four patients in each group died in the hospital.At the time of discharge, 65 (21 percent) of the 303 survivingpatients in the intervention group were classified as much betterin terms of their ability to perform basic activities of dailyliving, 39 (13 percent) as better, 151 (50 percent) as unchanged,22 (7 percent) as worse, and 26 (9 percent) as much worse. Inthe usual-care group, 40 (13 percent) of the 300 surviving patientswere classified as much better, 33 (11 percent) as better, 163(54 percent) as unchanged, 39 (13 percent) as worse, and 25(8 percent) as much worse (P = 0.009). The difference betweenthe groups remained significant (P =0.04) in a multivariablemodel in which we controlled for potentially confounding base-linecharacteristics of the patients. Lengths of stay and hospitalcharges were similar in the two groups.
Fewer patients assigned to the intervention group were dischargedto long-term care institutions (43 patients [14 percent], ascompared with 67 patients [22 percent] in the usual-care group;P = 0.01). Among the 493 patients discharged to private homes,similar proportions (about 10 percent) in the two groups wereadmitted to long-term care institutions during the three monthsafter discharge.
Conclusions Specific changes in the provision of acute hospitalcare can improve the ability of a heterogeneous group of acutelyill older patients to perform basic activities of daily livingat the time of discharge from the hospital and can reduce thefrequency of discharge to institutions for long-term care.
Source Information
From the Division of General Internal Medicine and Health Care Research (C.S.L., R.H.F.) and the Division of Geriatrics (C.S.L., R.M.P., R.H.F., J.K.), Department of Medicine, Case Western Reserve University; the University Hospitals of Cleveland (C.S.L., R.M.P., D.M.K., R.H.F., J.K.); and the Cleveland Veterans Affairs Medical Center (C.S.L., J.K.) all in Cleveland. Presented in part at the annual meetings of the American Federation for Clinical Research, Baltimore, May 14, 1992, and Washington, D.C., April 30May 1, 1993.
Address reprint requests to Dr. Landefeld at the Division of General Internal Medicine and Health Care Research, 111 G(W), Cleveland Veterans Affairs Medical Center, 10701 E. Blvd., Cleveland, OH 44106.
Di Bari, M., Balzi, D., Roberts, A. T., Barchielli, A., Fumagalli, S., Ungar, A., Bandinelli, S., De Alfieri, W., Gabbani, L., Marchionni, N.
(2009). Prognostic Stratification of Older Persons Based on Simple Administrative Data: Development and Validation of the "Silver Code," To Be Used in Emergency Department Triage. J Gerontol A Biol Sci Med Sci
0: glp043v3-glp043
[Abstract][Full Text]
Sleiman, I., Rozzini, R., Barbisoni, P., Morandi, A., Ricci, A., Giordano, A., Trabucchi, M.
(2009). Functional Trajectories During Hospitalization: A Prognostic Sign for Elderly Patients. J Gerontol A Biol Sci Med Sci
64A: 659-663
[Abstract][Full Text]
Brown, C. J., Roth, D. L., Allman, R. M., Sawyer, P., Ritchie, C. S., Roseman, J. M.
(2009). Trajectories of Life-Space Mobility After Hospitalization. ANN INTERN MED
150: 372-378
[Abstract][Full Text]
Klepin, H. D., Balducci, L.
(2009). Acute Myelogenous Leukemia in Older Adults. The Oncologist
14: 222-232
[Abstract][Full Text]
Siu, A. L., Spragens, L. H., Inouye, S. K., Morrison, R. S., Leff, B.
(2009). The Ironic Business Case For Chronic Care In The Acute Care Setting. Health Aff (Millwood)
28: 113-125
[Abstract][Full Text]
Friedman, S. M., Mendelson, D. A., Bingham, K. W., McCann, R. M.
(2008). Hazards of Hospitalization: Residence Prior to Admission Predicts Outcomes. Gerontologist
48: 537-541
[Abstract][Full Text]
Fernandez, H. M., Callahan, K. E., Likourezos, A., Leipzig, R. M.
(2008). House Staff Member Awareness of Older Inpatients' Risks for Hazards of Hospitalization. Arch Intern Med
168: 390-396
[Abstract][Full Text]
(2008). Functional Outcomes for Clinical Trials in Frail Older Persons: Time To Be Moving: Working Group on Functional Outcome Measures for Clinical Trials. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
63: 160-164
[Full Text]
Baer, M. R., Klepin, H. D., Artz, A. S.
(2008). Acute Leukemia in Older Adults: Are We Treating Too Much or Too Little?. Am Soc Clin Oncol Ed Book
2008: 216-223
[Abstract][Full Text]
Counsell, S. R., Callahan, C. M., Clark, D. O., Tu, W., Buttar, A. B., Stump, T. E., Ricketts, G. D.
(2007). Geriatric Care Management for Low-Income Seniors: A Randomized Controlled Trial. JAMA
298: 2623-2633
[Abstract][Full Text]
Boyd, C. M., Boult, C., Shadmi, E., Leff, B., Brager, R., Dunbar, L., Wolff, J. L., Wegener, S.
(2007). Guided Care for Multimorbid Older Adults: Kathleen Walsh Piercy, PhD, Editor. Gerontologist
47: 697-704
[Abstract][Full Text]
Wakefield, B. J., Holman, J. E.
(2007). Functional Trajectories Associated With Hospitalization in Older Adults. West J Nurs Res
29: 161-177
[Abstract]
de Morton, N. A, Keating, J. L, Jeffs, K.
(2007). The effect of exercise on outcomes for older acute medical inpatients compared with control or alternative treatments: a systematic review of randomized controlled trials. Clin Rehabil
21: 3-16
[Abstract]
Parker, S. G., Fadayevatan, R., Lee, S. D.
(2006). Acute hospital care for frail older people. Age Ageing
35: 551-552
[Full Text]
Rozzini, R., Sabatini, T., Trabucchi, M.
(2006). Non-invasive ventilation for respiratory failure in elderly patients. Age Ageing
35: 546-547
[Full Text]
Flood, K. L., Carroll, M. B., Le, C. V., Ball, L., Esker, D. A., Carr, D. B.
(2006). Geriatric Syndromes in Elderly Patients Admitted to an Oncology-Acute Care for Elders Unit. JCO
24: 2298-2303
[Abstract][Full Text]
Pedone, C., Ercolani, S., Catani, M., Maggio, D., Ruggiero, C., Quartesan, R., Senin, U., Mecocci, P., Cherubini, A., on Behalf of the GIFA Study Group,
(2005). Elderly Patients With Cognitive Impairment Have a High Risk for Functional Decline During Hospitalization: The GIFA Study. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
60: 1576-1580
[Abstract][Full Text]
Rozzini, R., Sabatini, T., Cassinadri, A., Boffelli, S., Ferri, M., Barbisoni, P., Frisoni, G. B., Trabucchi, M.
(2005). Relationship Between Functional Loss Before Hospital Admission and Mortality in Elderly Persons With Medical Illness. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
60: 1180-1183
[Abstract][Full Text]
Boyd, C. M., Xue, Q.-L., Guralnik, J. M., Fried, L. P.
(2005). Hospitalization and Development of Dependence in Activities of Daily Living in a Cohort of Disabled Older Women: The Women's Health and Aging Study I. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
60: 888-893
[Abstract][Full Text]
Ellis, G., Langhorne, P.
(2005). Comprehensive geriatric assessment for older hospital patients. Br Med Bull
71: 45-59
[Abstract][Full Text]
Gill, T. M., Allore, H. G., Holford, T. R., Guo, Z.
(2004). Hospitalization, Restricted Activity, and the Development of Disability Among Older Persons. JAMA
292: 2115-2124
[Abstract][Full Text]
Neilson, E. G., Johnson, K. B., Rosenbloom, S. T., Dupont, W. D., Talbert, D., Giuse, D. A., Kaiser, A., Miller, R. A., the Resource Utilization Committee*,
(2004). The Impact of Peer Management on Test-Ordering Behavior. ANN INTERN MED
141: 196-204
[Abstract][Full Text]
Kleinpell, R. M.
(2004). Randomized Trial of an Intensive Care Unit-Based Early Discharge Planning Intervention for Critically Ill Elderly Patients. Am J Crit Care
13: 335-345
[Abstract][Full Text]
Gill, T. M., Allore, H., Guo, Z.
(2004). The Deleterious Effects of Bed Rest Among Community-Living Older Persons. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
59: M755-M761
[Abstract][Full Text]
Kiely, D. K., Bergmann, M. A., Jones, R. N., Murphy, K. M., Orav, E. J., Marcantonio, E. R.
(2004). Characteristics Associated With Delirium Persistence Among Newly Admitted Post-Acute Facility Patients. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
59: M344-M349
[Abstract][Full Text]
Andreoli, P. B. d. A., Citero, V. d. A., Mari, J. d. J.
(2003). A Systematic Review of Studies of the Cost-Effectiveness of Mental Health Consultation-Liaison Interventions in General Hospitals. Psychosomatics
44: 499-507
[Abstract][Full Text]
Fried, L. P.
(2003). Establishing Benchmarks for Quality Care for an Aging Population: Caring for Vulnerable Older Adults. ANN INTERN MED
139: 784-786
[Full Text]
Landefeld, C S.
(2003). Improving Health Care for Older Persons. ANN INTERN MED
139: 421-424
[Abstract][Full Text]
Devlin, A. S., Arneill, A. B.
(2003). Health Care Environments and Patient Outcomes: A Review of the Literature. Environment and Behavior
35: 665-694
[Abstract]
Tsilimingras, D., Rosen, A. K., Berlowitz, D. R.
(2003). Review Article: Patient Safety in Geriatrics: A Call for Action. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
58: M813-819
[Abstract][Full Text]
Flaherty, J. H., Stalvey, B., Rubenstein, L.
(2003). Guest Editorial: A Consensus Statement on Nonemergent Medical Transportation Services for Older Persons. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
58: M826-831
[Full Text]
Rozzini, R., Sabatini, T., Frisoni, G. B., Trabucchi, M.
(2003). Frailty Is a Strong Modulator of Heart Failure-Associated Mortality. Arch Intern Med
163: 737-738
[Full Text]
Rozzini, R., Sabatini, T., Trabucchi, M.
(2003). THE NETWORK FOR ELDERLY CARE IN ITALY: ONLY A CORRECT USE OF ACUTE WARDS ALLOWS AN OVERALL FUNCTIONING OF THE HEALTH CARE SYSTEM. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
58: M190-191
[Full Text]
Sands, L. P., Yaffe, K., Covinsky, K., Chren, M.-M., Counsell, S., Palmer, R., Fortinsky, R., Landefeld, C. S.
(2003). Cognitive Screening Predicts Magnitude of Functional Recovery From Admission to 3 Months After Discharge in Hospitalized Elders. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
58: M37-45
[Abstract][Full Text]
Binder, E. F., Kruse, R. L., Sherman, A. K., Madsen, R., Zweig, S. C., D'Agostino, R., Mehr, D. R.
(2003). Predictors of Short-Term Functional Decline in Survivors of Nursing Home-Acquired Lower Respiratory Tract Infection. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
58: M60-67
[Abstract][Full Text]
Kane, R. L.
(2002). The Future History of Geriatrics: Geriatrics at the Crossroads. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M803-805
[Full Text]
Flaherty, J. H.
(2002). The Adolescence of Geriatrics. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M808-811
[Full Text]
Thomas, D. R.
(2002). Guest Editorial: Focus on Functional Decline in Hospitalized Older Adults. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M567-568
[Full Text]
Mezey, M., Fulmer, T.
(2002). The Future History of Gerontological Nursing. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M438-441
[Abstract][Full Text]
Sands, L. P., Yaffe, K., Lui, L.-Y., Stewart, A., Eng, C., Covinsky, K.
(2002). The Effects of Acute Illness on ADL Decline Over 1 Year in Frail Older Adults With and Without Cognitive Impairment. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M449-454
[Abstract][Full Text]
Bortz, W. M. II
(2002). A Conceptual Framework of Frailty: A Review. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
57: M283-288
[Abstract][Full Text]
Rozzini, R., Sabatini, T., Frisoni, G. B., Trabucchi, M., Bula, C. J., Wietlisbach, V., Burnand, B., Yersin, B.
(2002). Depressive Symptoms and Negative Outcomes in Older Hospitalized Patients. Arch Intern Med
162: 948-949
[Full Text]
Cohen, H. J., Feussner, J. R., Weinberger, M., Carnes, M., Hamdy, R. C., Hsieh, F., Phibbs, C., Courtney, D., Lyles, K. W., May, C., McMurtry, C., Pennypacker, L., Smith, D. M., Ainslie, N., Hornick, T., Brodkin, K., Lavori, P.
(2002). A Controlled Trial of Inpatient and Outpatient Geriatric Evaluation and Management. NEJM
346: 905-912
[Abstract][Full Text]
Rozzini, R., Sabatini, T., Frisoni, G. B., Trabucchi, M., Jiang, W., Krishnan, R. R., O'Connor, C. M.
(2002). Depression and Major Outcomes in Older Patients With Heart Failure. Arch Intern Med
162: 362-364
[Full Text]
Fried, T. R., Bradley, E. H., Williams, C. S., Tinetti, M. E.
(2001). Functional Disability and Health Care Expenditures for Older Persons. Arch Intern Med
161: 2602-2607
[Abstract][Full Text]
Rozzini, R., Sabatini, T., Trabucchi, M.
(2001). Prediction of 6-Month Mortality Among Older Hospitalized Adults. JAMA
286: 1315-1316
[Full Text]
Daley, J.
(2001). A 58-Year-Old Woman Dissatisfied With Her Care. JAMA
285: 2629-2635
[Full Text]
Boult, C., Kane, R. L, Brown, R.
(2000). Managed care of chronically ill older people: the US experience. BMJ
321: 1011-1014
[Full Text]
Rothschild, J. M., Bates, D. W., Leape, L. L.
(2000). Preventable Medical Injuries in Older Patients. Arch Intern Med
160: 2717-2728
[Abstract][Full Text]
Cassel, C. K.
(2000). In Defense of a Department of Geriatrics. ANN INTERN MED
133: 297-301
[Abstract][Full Text]
Pine, Z. M., Gurland, B., Chren, M.-M.
(2000). Report of Having Slowed Down: Evidence for the Validity of a New Way to Inquire About Mild Disability in Elders. Journals of Gerontology Series A: Biological Sciences and Medical Sciences
55: 378M-383
[Abstract][Full Text]
Beissner, K. L, Collins, J. E, Holmes, H.
(2000). Muscle Force and Range of Motion as Predictors of Function in Older Adults. ptjournal
80: 556-563
[Abstract][Full Text]
Barrick, C., Karuza, J., Levitt, J.
(1999). Impacting Quality: Assessment of a Hospital-Based Geriatric Acute Care Unit. American Journal of Medical Quality
14: 133-137
[Abstract]
Covinsky, K. E., Kahana, E., Chin, M. H., Palmer, R. M., Fortinsky, R. H., Landefeld, C. S.
(1999). Depressive Symptoms and 3-Year Mortality in Older Hospitalized Medical Patients. ANN INTERN MED
130: 563-569
[Abstract][Full Text]
Naylor, M. D., Brooten, D., Campbell, R., Jacobsen, B. S., Mezey, M. D., Pauly, M. V., Schwartz, J. S.
(1999). Comprehensive Discharge Planning and Home Follow-up of Hospitalized Elders: A Randomized Clinical Trial. JAMA
281: 613-620
[Abstract][Full Text]
Inouye, S. K., Peduzzi, P. N., Robison, J. T., Hughes, J. S., Horwitz, R. I., Concato, J.
(1998). Importance of Functional Measures in Predicting Mortality Among Older Hospitalized Patients. JAMA
279: 1187-1193
[Abstract][Full Text]
Wade, D. T
(1998). Editorial. Clin Rehabil
12: 95-97
Wilkinson, T., Buhrkuhl, D., Sainsbury, R.
(1997). Assessing and restoring function in elderly people -- more than rehabilitation. Clin Rehabil
11: 321-328
[Abstract]
Ferrucci, L., Guralnik, J. M., Pahor, M., Corti, M. C., Havlik, R. J.
(1997). Hospital Diagnoses, Medicare Charges, and Nursing Home Admissions in the Year When Older Persons Become Severely Disabled. JAMA
277: 728-734
[Abstract]
Applegate, W. B., Burns, R.
(1996). Geriatric Medicine. JAMA
275: 1812-1813
[Abstract]
Sager, M. A., Franke, T., Inouye, S. K., Landefeld, C. S., Morgan, T. M., Rudberg, M. A., Siebens, H., Winograd, C. H.
(1996). Functional Outcomes of Acute Medical Illness and Hospitalization in Older Persons. Arch Intern Med
156: 645-652
[Abstract]
Greganti, M. A., Hanson, L. C.
(1996). Comprehensive Geriatric Assessment: Where Do We Go From Here?. Arch Intern Med
156: 15-17
[Abstract]
Manton, K. G., Vaupel, J. W.
(1995). Survival after the Age of 80 in the United States, Sweden, France, England, and Japan. NEJM
333: 1232-1235
[Abstract][Full Text]
Campion, E. W.
(1995). The Value of Geriatric Interventions. NEJM
332: 1376-1378
[Full Text]