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Correction to Dec and Fuster, N Engl J Med 331(23):1564-1575 December 8, 1994.

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Volume 332:1384-1386 May 18, 1995 Number 20
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Idiopathic Dilated Cardiomyopathy

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 by Dec, G. W.
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 by Dec, G. W.
To the Editor: Dec and Fuster (Dec. 8 issue)1 categorized the use of beta-blockers in patients with idiopathic dilated cardiomyopathy as investigational. There is now sufficient evidence to support their use as adjunctive therapy. Numerous clinical trials have evaluated the use of beta-blockers in conjunction with angiotensin-converting–enzyme inhibitors, nitrates, diuretics, and digoxin in patients with idiopathic dilated cardiomyopathy and have found improvements in ejection fraction, cardiac index, and New York Heart Association class and a decreased number of hospital admissions and cardiac transplantations.2,3,4 However, there have been trials5,6 that did not show such improvements. This is probably because patients were . . . [Full Text of this Article]

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