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Correspondence
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Volume 332:1578-1579 June 8, 1995 Number 23
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Family History and Colorectal Cancer

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 by Fuchs, C. S.
To the Editor: On the basis of a prospective study, Fuchs and colleagues (Dec. 22 issue)1 estimate that the relative risk of colorectal cancer is 5.37 for people younger than 45 years of age who have one or more affected first-degree relatives. In an attempt to identify families with colon cancer, we have obtained detailed information on family history from 17 unselected patients with very-early-onset colon cancer (onset at the age of 39 or younger) through the records of the tumor registry of the Royal Victoria Hospital in Montreal. None of the patients were from families with polyposis syndromes. Among . . . [Full Text of this Article]

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