Over the past 20 years, the results of well-designed randomizedtrials in patients with deep-vein thrombosis have provided reliableinformation about the treatment of this common disorder. Patientswith deep-vein thrombosis should receive adequate doses of heparinfor a minimum of five days.1,2,3 When heparin is stopped, patientsshould continue to receive oral anticoagulant therapy; the incidenceof recurrent deep-vein thrombosis in the first three monthsis over 25 percent without such treatment, but less than 4 percentamong treated patients.4,5
Progress has been made in determining the optimal intensityof oral anticoagulant therapy,6 but the optimal duration oftreatment . . . [Full Text of this Article]
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