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A correction has been published: N Engl J Med 1995;333(16):1091.

Review Article
Current Concepts
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Volume 332:1767-1772 June 29, 1995 Number 26
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Chronic Urticaria
Malcolm W. Greaves

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Though rarely life-threatening, widespread urticaria and its associated angioedema can be both debilitating and frightening. In some cases, lingual swelling requires treatment with epinephrine. Although accurate data on the prevalence of urticaria are unavailable, 15 to 23 percent of the U.S. population may have had this condition,1,2 which in many cases is prolonged and relapsing. On the basis of published data,3 a similar prevalence in the United Kingdom seems probable. Chronic urticaria is likely to be present at some time in about 25 percent of patients with urticaria. By chronic urticaria, I mean the occurrence of widespread wheals daily or . . . [Full Text of this Article]

Clinical Presentation

Histopathological Features

Pathophysiologic Features

Autoimmune Mast-Cell Disease

Other Causative Factors

Diagnosis

Treatment


Source Information

From the St. John's Institute of Dermatology, United Medical and Dental Schools, St. Thomas's Hospital, Lambeth Palace Rd., London SE1 7EH, United Kingdom, where reprint requests should be addressed to Dr. Greaves.

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