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Previous Volume 332:193 January 19, 1995 Number 3 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: In his letter (Sept. 15 issue),¹ Huston described bilateral rupture of the Achilles tendon in a patient treated with enoxacin and prednisone. Although no cases of tendon rupture were reported to the Food and Drug Administration (FDA) during premarketing clinical trials of fluoroquinolones currently on the market, the following information from the FDA's Postmarketing Spontaneous Reporting System does support the need for increased awareness of this adverse event.

As of October 1994, 25 cases of tendon rupture were reported, 22 of them occurring outside the United States. The patients whose ages were reported ranged from 33 to . . . [Full Text of this Article]

References

This article has been cited by other articles:

• van der Linden, P. D., Sturkenboom, M. C. J. M., Herings, R. M. C., Leufkens, H. M. G., Rowlands, S., Stricker, B. H. Ch. (2003). Increased Risk of Achilles Tendon Rupture With Quinolone Antibacterial Use, Especially in Elderly Patients Taking Oral Corticosteroids. Arch Intern Med 163: 1801-1807 [Abstract] [Full Text]  
• van der Linden, P D, Sturkenboom, M C J M, Herings, R M C, Leufkens, H G M, Stricker, B H C. (2002). Fluoroquinolones and risk of Achilles tendon disorders: case-control study. BMJ 324: 1306-1307 [Full Text]  
• Chhajed, P.N., Plit, M.L., Hopkins, P.M., Malouf, M.A., Glanville, A.R. (2002). Achilles tendon disease in lung transplant recipients: association with ciprofloxacin. Eur Respir J 19: 469-471 [Abstract] [Full Text]  
• Williams, R. J. III, Attia, E., Wickiewicz, T. L., Hannafin, J. A. (2000). The Effect of Ciprofloxacin On Tendon, Paratenon, and Capsular Fibroblast Metabolism. Am J Sports Med 28: 364-369 [Abstract] [Full Text]  
• Simonin, M.-A., Gegout-Pottie, P., Minn, A., Gillet, P., Netter, P., Terlain, B. (2000). Pefloxacin-Induced Achilles Tendon Toxicity in Rodents: Biochemical Changes in Proteoglycan Synthesis and Oxidative Damage to Collagen. Antimicrob. Agents Chemother. 44: 867-872 [Abstract] [Full Text]  
• Shakibaei, M., Pfister, K., Schwabe, R., Vormann, J., Stahlmann, R. (2000). Ultrastructure of Achilles Tendons of Rats Treated with Ofloxacin and Fed a Normal or Magnesium-Deficient Diet. Antimicrob. Agents Chemother. 44: 261-266 [Abstract] [Full Text]  
• MAFFULLI, N. (1999). Current Concepts Review - Rupture of the Achilles Tendon. JBJS 81: 1019-36 [Full Text]