FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 332:312-317 February 2, 1995 Number 5 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF Purchase this article Letters Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited Related Article by Wiesenfeld, H. C. PubMed Citation

Fifteen percent of couples are subfertile — that is, they have less-than-normal fertility. In approximately 30 percent of the cases, an important abnormality is identified in only the man, and in another 20 percent abnormalities are detected in both partners. Thus, there is a male factor in infertility in half of the couples. The evaluation should begin with a complete history taking, physical examination, and appropriate laboratory tests. Unfortunately, even after a thorough evaluation, the cause of a man's lack of normal fertility usually remains unknown. Since it is very difficult to develop a rational treatment plan to correct a . . . [Full Text of this Article]

Lifestyle Factors

Failure of Emission

Retrograde Ejaculation

Abnormalities of Semen

Infection

Varicocele

Microsurgical Correction

Vasovasostomy

Microsurgical Vasoepididymostomy

Immunologic Infertility

Hypogonadotropic Hypogonadism

Idiopathic Oligospermia and Asthenospermia

Medical Therapy

            Testosterone-Rebound Therapy

            Gonadotropin-Releasing Hormone

            Human Chorionic Gonadotropin

            Clomiphene Citrate and Tamoxifen

            Testolactone

            Mesterolone

Semen Processing and Intrauterine Insemination

Assisted-Reproduction Techniques

Source Information

From the Department of Urology, University of Virginia Hospital, Health Sciences Center Box 422, Charlottesville, VA 22908, where reprint requests should be addressed to Dr. Howards.

References

Related Letters:

Male Infertility
Wiesenfeld H. C., Amelar R. D., Dubin L., Schoenfeld C., Tur-Kaspa I., Maor Y., Dor J., Howards S. S.
Extract | Full Text  
N Engl J Med 1995; 332:1790-1791, Jun 29, 1995. Correspondence

This article has been cited by other articles:

• Mackey, W. C., Immerman, R. S. (2007). Sexually Transmitted Disease and Gender Roles: An Index of Cultural Evolution. Cross-Cultural Research 41: 46-65 [Abstract]  
• Tohda, A., Okuno, T., Matsumiya, K., Okabe, M., Kishikawa, H., Dohmae, K., Okuyama, A., Nishimune, Y. (2002). Restoration of Spermatogenesis and Fertility in Azoospermic Mutant Mice by Suppression and Reelevation of Testosterone Followed by Intracytoplasmic Sperm Injection. Biol. Reprod. 66: 85-90 [Abstract] [Full Text]  
• Mackey, W. C., Immerman, R. S. (2001). Restriction of Sexual Activity as a Partial Function of Disease Avoidance: A Cultural Response to Sexually Transmitted Diseases. Cross-Cultural Research 35: 400-423 [Abstract]  
• Hayes, F. J., Pitteloud, N., DeCruz, S., Crowley, W. F. Jr., Boepple, P. A. (2001). Importance of Inhibin B in the Regulation of FSH Secretion in the Human Male. J. Clin. Endocrinol. Metab. 86: 5541-5546 [Abstract] [Full Text]  
• Chia, S.-E., Lim, S.-T. A., Ho, L.-M., Tay, S.-K. (2001). Monthly variation in human semen quality in male partners of infertile women in the tropics. Hum Reprod 16: 277-281 [Abstract] [Full Text]  
• Cagnacci, A., Maxia, N., Volpe, A. (1999). Diurnal variation of semen quality in human males. Hum Reprod 14: 106-109 [Abstract] [Full Text]  
• McBride, P., Schrott, H. G., Plane, M. B., Underbakke, G., Brown, R. L. (1998). Primary Care Practice Adherence to National Cholesterol Education Program Guidelines for Patients With Coronary Heart Disease. Arch Intern Med 158: 1238-1244 [Abstract] [Full Text]  
• Blanchard, K. T., Lee, J., Boekelheide, K. (1998). Leuprolide, a Gonadotropin-Releasing Hormone Agonist, Reestablishes Spermatogenesis After 2,5-Hexanedione-Induced Irreversible Testicular Injury in the Rat, Resulting in Normalized Stem Cell Factor Expression. Endocrinology 139: 236-244 [Abstract] [Full Text]  
• Sampietro, T., Tuoni, M., Ferdeghini, M., Ciardi, A., Marraccini, P., Prontera, C., Sassi, G., Taddei, M., Bionda, A. (1997). Plasma Cholesterol Regulates Soluble Cell Adhesion Molecule Expression in Familial Hypercholesterolemia. Circulation 96: 1381-1385 [Abstract] [Full Text]  
• Gnessi, L., Fabbri, A., Spera, G. (1997). Gonadal Peptides as Mediators of Development and Functional Control of the Testis: An Integrated System with Hormones and Local Environment. Endocr. Rev. 18: 541-609 [Abstract] [Full Text]  
• Wiesenfeld, H. C., Amelar, R. D., Dubin, L., Schoenfeld, C., Tur-Kaspa, I., Maor, Y., Dor, J., Howards, S. S. (1995). Male Infertility. NEJM 332: 1790-1791 [Full Text]