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Previous Volume 332:390-392 February 9, 1995 Number 6 Next

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Whipple's disease is both rare and enigmatic. It usually presents in middle-aged men, but in the 80 or so years since it was first described, fewer than 10 cases per year have been reported in the world's literature.¹ The most common clinical presentation is a malabsorption syndrome, although patients may have severe arthralgias for years before diarrhea develops. Cardiac and central nervous system involvement is also common. Patients may present with fever of undetermined cause, a sarcoidosis-like illness, or a wasting syndrome. Because the illness is insidious in its onset, has a varied clinical presentation, and is rare, it is . . . [Full Text of this Article]

References

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