Exposures to blood-borne pathogens pose a serious occupationalthreat to health care workers. Safer needle devices for performingphlebotomy and other procedures and universal infection-controlprecautions will not completely eliminate the risk, and prophylactictreatment will remain an important component of prevention efforts.This article will review post-exposure care for the three blood-bornepathogens that are most commonly involved in occupational transmission hepatitis B virus (HBV), hepatitis C virus (HCV), andhuman immunodeficiency virus (HIV).
Assessment of Exposure
Occupational exposures include contact of the eyes, mouth, othermucous membranes, or broken skin and parenteral contact withblood or other potentially infectious materials . . . [Full Text of this Article]
Hepatitis B Virus
Risk of Transmission
Indications for Post-Exposure Prophylaxis
Post-Exposure Therapy
Advice and Follow-Up after Exposure to HBV
Hepatitis C Virus
Risk of Transmission
Post-Exposure Therapy
Advice and Follow-Up
Human Immunodeficiency Virus
Risk of Transmission
Approaches to Post-Exposure Prophylaxis
Efficacy and Toxicity of Zidovudine in Health Care Workers
Current Recommendations
Advice and Follow-Up
Future Goals
Source Information
From the Departments of Medicine (Infectious Diseases) and Epidemiology and Biostatistics, University of California, San Francisco, and the Epidemiology and Prevention Interventions Center, San Francisco General Hospital both in San Francisco.
Address reprint requests to Dr. Gerberding at Medical Service 5H-22, San Francisco General Hospital, 1001 Potrero Ave., San Francisco, CA 94110.
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