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Previous Volume 332:576-579 March 2, 1995 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Arterial dissection occurs when blood enters a vessel wall through an intimal tear and a false lumen of blood is formed within the media.^1,2 The artery most commonly affected by dissection is the aorta,¹ followed by the renal^3,4 and extracranial internal carotid^2,5 arteries.

The pathogenesis of arterial dissection is incompletely understood, but a primary arteriopathy is frequently suspected, especially in younger patients. The possibility of a genetic predisposition to such an arteriopathy is supported by the familial occurrence of arterial dissections^6,7,8,9 and their association with various heritable connective-tissue disorders.^10,11 In our experience with cervical-artery dissections, the nature of the arteriopathy . . . [Full Text of this Article]

Case Reports

Family A

            Propositus

            Family History

Family B

            Propositus

            Family History

Discussion

Source Information

From the Departments of Neurologic Surgery (W.I.S., D.G.P.), Medical Genetics (V.V.M.), Neurology (B.M.), and Dermatology (H.O.P.), Mayo Clinic, Rochester, Minn.

Address reprint requests to Dr. Schievink at the Mayo Clinic, Department of Neurologic Surgery, 200 First St., SW, Rochester, MN 55905.

References

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• Nkomo, V. T., Enriquez-Sarano, M., Ammash, N. M., Melton, L. J. III, Bailey, K. R., Desjardins, V., Horn, R. A., Tajik, A. J. (2003). Bicuspid Aortic Valve Associated With Aortic Dilatation: A Community-Based Study. Arterioscler. Thromb. Vasc. Bio. 23: 351-356 [Abstract] [Full Text]  
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• Schievink, W. I., Mokri, B., Piepgras, D. G., Kuiper, J. D. (1996). Recurrent Spontaneous Arterial Dissections : Risk in Familial Versus Nonfamilial Disease. Stroke 27: 622-624 [Abstract] [Full Text]  
• Schievink, W. I., Mokri, B. (1995). Familial Aorto-Cervicocephalic Arterial Dissections and Congenitally Bicuspid Aortic Valve. Stroke 26: 1935-1940 [Abstract] [Full Text]