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Previous Volume 333:32-41 July 6, 1995 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Despite a marked decline in the incidence of gastric carcinoma in many industrialized nations, cancer of the stomach remains the second most common cause of cancer-related deaths in the world.¹ In 1995, 22,800 Americans will be given a diagnosis of gastric carcinoma, and 14,700 will die of the disease.² This review discusses recent developments in our understanding of the epidemiology and pathogenesis of gastric carcinoma, methods of diagnosis and staging, and approaches to treatment and palliation.

Epidemiology and Biology

Incidence

In 1930, gastric carcinoma was the leading cause of cancer-related deaths among American men and the third most common cause among women.³ Over the . . . [Full Text of this Article]

Pathological Features

Precursor Conditions

Genetic and Environmental Risk Factors

Molecular Features

Diagnosis

Clinical Presentation

Diagnostic Studies

Tumor Markers

Screening

Staging and Prognosis

Treatment

Surgery

Radiotherapy

Chemotherapy

Source Information

From the Division of Medical Oncology, Dana-Farber Cancer Institute (C.S.F., R.J.M.); the Channing Laboratory, Department of Medicine, Brigham and Women's Hospital (C.S.F.); and Harvard Medical School (C.S.F., R.J.M.) -- all in Boston.

Address reprint requests to Dr. Fuchs at the Dana-Farber Cancer Institute, 44 Binney St., Boston, MA 02115.

References

Related Letters:

Gastric Carcinoma
Lowy A. M., Mansfield P. F., Greene F. L., Kullmann F., McClelland M., Fuchs C. S., Mayer R. J.
Extract | Full Text  
N Engl J Med 1995; 333:1426-1428, Nov 23, 1995. Correspondence

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