FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 333:54-55 July 6, 1995 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited PubMed Citation

Since its discovery more than 50 years ago, warfarin has endured as a remarkable drug and is now the 14th-largest-selling medication in the United States. The efficacy of oral anticoagulant therapy in treating and providing prophylaxis against venous thromboembolism and in preventing arterial thromboembolism in patients with atrial fibrillation or prosthetic heart valves is generally accepted. Another indication for warfarin was recently approved by the Food and Drug Administration: the prevention of death, venous thromboembolism, and recurrent infarction after acute myocardial infarction. In relation to other widely prescribed medications, warfarin remains inexpensive (when the costs of laboratory monitoring are disregarded).

. . . [Full Text of this Article]

References

This article has been cited by other articles:

• Guang, Y., Zhen-jie, C., Wei Yong, L., Tong, L., Ying, L. (2002). Evaluation of clinical treatment of atrial fibrillation associated with rheumatic mitral valve disease by radiofrequency ablation. Eur. J. Cardiothorac. Surg. 21: 249-254 [Abstract] [Full Text]  
• Evans, A., Kalra, L. (2001). Are the Results of Randomized Controlled Trials on Anticoagulation in Patients With Atrial Fibrillation Generalizable to Clinical Practice?. Arch Intern Med 161: 1443-1447 [Abstract] [Full Text]  
• Ngui, J. S., Chen, Q., Shou, M., Wang, R. W., Stearns, R. A., Baillie, T. A., Tang, W. (2001). In Vitro Stimulation of Warfarin Metabolism by Quinidine: Increases in the Formation of 4'- and 10-Hydroxywarfarin. Drug Metab. Dispos. 29: 877-886 [Abstract] [Full Text]  
• Raanani, E., Albage, A., David, T. E., Yau, T. M., Armstrong, S. (2001). The efficacy of the Cox/maze procedure combined with mitral valve surgery: a matched control study. Eur. J. Cardiothorac. Surg. 19: 438-442 [Abstract] [Full Text]  
• Handa, N., Schaff, H. V., Morris, J. J., Anderson, B. J., Kopecky, S. L., Enriquez-Sarano, M. (1999). OUTCOME OF VALVE REPAIR AND THE COX MAZE PROCEDURE FOR MITRAL REGURGITATION AND ASSOCIATED ATRIAL FIBRILLATION. J. Thorac. Cardiovasc. Surg. 118: 628-635 [Abstract] [Full Text]  
• Chiquette, E., Amato, M. G., Bussey, H. I. (1998). Comparison of an Anticoagulation Clinic With Usual Medical Care: Anticoagulation Control, Patient Outcomes, and Health Care Costs. Arch Intern Med 158: 1641-1647 [Abstract] [Full Text]  
• Stafford, R. S., Singer, D. E. (1996). National Patterns of Warfarin Use in Atrial Fibrillation. Arch Intern Med 156: 2537-2541 [Abstract]  
• Nistal, J. F., Hurle, A., Revuelta, J. M., Gandarillas, M. (1996). CLINICAL EXPERIENCE WITH THE CARBOMEDICS VALVE: EARLY RESULTS WITH A NEW BILEAFLET MECHANICAL PROSTHESIS. J. Thorac. Cardiovasc. Surg. 112: 59-68 [Abstract] [Full Text]  
• Fitzmaurice, D A, Hobbs, F D R, Murray, J A (1996). Monitoring oral anticoagulation in primary care. BMJ 312: 1431-1432 [Full Text]  
• Brechtelsbauer, D. A. (1995). New Knowledge, Old Patients. Arch Fam Med 4: 1014-1016 [Abstract]  
• (1995). OPTIMAL ANTICOAGULATION DEFINED FOR TWO CLINICAL SETTINGS. JWatch General 1995: 4-4 [Full Text]