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Editorial
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Volume 333:658-659 September 7, 1995 Number 10
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New Therapies for Cytomegalovirus Retinitis

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Cytomegalovirus retinitis is a devastating complication that may occur in as many as 40 percent of patients with the acquired immunodeficiency syndrome (AIDS).1 Lifelong daily intravenous infusions of ganciclovir or foscarnet can usually control cytomegalovirus retinitis,2 but these therapies are toxic, expensive, and inconvenient. they are also associated with the risk of catheter-related infection and sepsis. An orally administered anticytomegalovirus drug has therefore been a major goal.

In this issue of the Journal, Drew and associates3 describe an important study of oral ganciclovir for the treatment of cytomegalovirus retinitis. The results, which corroborate those of other investigators,4 suggest that the . . . [Full Text of this Article]

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