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Volume 333:727-730 September 14, 1995 Number 11
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Bone Marrow Transplantation versus Chemotherapy in Non-Hodgkin's Lymphoma

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by Walker, A. M.
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by The International Non-Hodgkin's Lymphoma Prognostic Factors Project
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by Verdonck, L. F.
To the Editor: In their study of the efficacy of high-dose chemotherapy and autologous bone marrow transplantation in patients with non-Hodgkin's lymphoma who respond slowly to chemotherapy, Verdonck et al. (April 20 issue)1 used response criteria that may have influenced the outcome. A variety of criteria have been proposed to assess response in patients with lymphoma, but the most widely accepted are those ratified at the Cotswolds meeting,2 which define a partial remission as "a decrease by at least 50 percent in the sum of the products of the largest perpendicular diameters of all measurable lesions." In contrast, Verdonck et . . . [Full Text of this Article]

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