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Volume 333:808 September 21, 1995 Number 12
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Familial and Hereditary Tumors

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(Recent Results in Cancer Research. [136].) By M. Ponz de Leon. 347 pp., illustrated. New York, Springer-Verlag, 1995. DM198. ISBN 0-387-57663-9.

Every week it seems that a new cancer gene is discovered, and every month, a suspected carcinogen. Who will summarize this avalanche of information and integrate it for wide use?

With Familial and Hereditary Tumors, Dr. Ponz de Leon, professor of internal medicine at the University of Modena in Italy, has made such an attempt. At the outset, he hypothesizes "that almost invariably cancer develops because of a close interaction between genes and exogenous agents or, in other words, that an inherited condition renders individuals highly susceptible to tumors, but that these usually occur owing to the effect of exogenous . . . [Full Text of this Article]




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