Of all the preventive measures available to practitioners today,few are as medically and economically compelling as vaccinationagainst influenza. The disease it prevents is associated with10,000 to 40,000 excess deaths and more than 150,000 excesshospitalizations annually,1,2,3 most of which result from theexacerbation of preexisting medical conditions.1,2 Althoughtheir intensity and distribution vary, community-wide outbreaksof influenza routinely cause widespread absenteeism in businesses,schools, and day-care centers during the winter months and havebeen estimated to cost consumers in this country at least $12billion annually in direct and indirect expenses.3
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