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Correspondence
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Volume 333:1006-1007 October 12, 1995 Number 15
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Heparin-Induced Thrombocytopenia

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 by Warkentin, T. E.
To the Editor: We disagree that the study by Warkentin et al. (May 18 issue)1 identified a difference in outcome favoring the use of low-molecular-weight heparin. Their initial study of the identical patient population found no statistically significant difference in thrombotic events, incidence of venous thrombosis, episodes of major bleeding, or red-cell–transfusion requirements between the group given standard heparin and the group given low-molecular-weight heparin.2

From both studies (really the same study) one can conclude only that heparin-induced thrombocytopenia is a marker of thrombotic disease, because the authors do not demonstrate that thrombosis as a consequence of heparin-induced thrombocytopenia has . . . [Full Text of this Article]

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